Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report

Pregnancy in a patient with Marfan syndrome is associated with risks, including cardiovascular complications. The hemodynamic changes of pregnancy during delivery are deleterious to Marfan syndrome patients. This case describes a Marfan syndrome parturient with dilated aortic root >45 mm who unde...

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Main Authors: Matea Malinovic, Kimberly Babiash, Felecia Newton
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2023-01-01
Series:Journal of Obstetric Anaesthesia and Critical Care
Subjects:
Online Access:http://www.joacc.com/article.asp?issn=2249-4472;year=2023;volume=13;issue=1;spage=106;epage=108;aulast=Malinovic
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author Matea Malinovic
Kimberly Babiash
Felecia Newton
author_facet Matea Malinovic
Kimberly Babiash
Felecia Newton
author_sort Matea Malinovic
collection DOAJ
description Pregnancy in a patient with Marfan syndrome is associated with risks, including cardiovascular complications. The hemodynamic changes of pregnancy during delivery are deleterious to Marfan syndrome patients. This case describes a Marfan syndrome parturient with dilated aortic root >45 mm who underwent neuraxial anesthesia and cesarean delivery. Anesthetic management focused on reducing hypertension and shear forces on the ascending aorta. A combined spinal-epidural with a reduced dose of hyperbaric bupivacaine was utilized for cesarean delivery. Multidisciplinary approaches are vital in the management of Marfan syndrome pregnancy and cardiovascular complications must be considered when planning for delivery and postpartum management. Anesthetic management must consider the hemodynamic changes in pregnancy and severity of Marfan syndrome cardiovascular involvement in the parturient as well as neonatal risks. Guideline development concerning anesthetic management for both the timing of delivery and aortic repair postpartum would be beneficial to Marfan syndrome parturients.
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spelling doaj.art-9d35317e6e7049319d40eca1ea6e053a2023-03-21T11:20:35ZengWolters Kluwer Medknow PublicationsJournal of Obstetric Anaesthesia and Critical Care2249-44722023-01-0113110610810.4103/JOACC.JOACC_31_22Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case reportMatea MalinovicKimberly BabiashFelecia NewtonPregnancy in a patient with Marfan syndrome is associated with risks, including cardiovascular complications. The hemodynamic changes of pregnancy during delivery are deleterious to Marfan syndrome patients. This case describes a Marfan syndrome parturient with dilated aortic root >45 mm who underwent neuraxial anesthesia and cesarean delivery. Anesthetic management focused on reducing hypertension and shear forces on the ascending aorta. A combined spinal-epidural with a reduced dose of hyperbaric bupivacaine was utilized for cesarean delivery. Multidisciplinary approaches are vital in the management of Marfan syndrome pregnancy and cardiovascular complications must be considered when planning for delivery and postpartum management. Anesthetic management must consider the hemodynamic changes in pregnancy and severity of Marfan syndrome cardiovascular involvement in the parturient as well as neonatal risks. Guideline development concerning anesthetic management for both the timing of delivery and aortic repair postpartum would be beneficial to Marfan syndrome parturients.http://www.joacc.com/article.asp?issn=2249-4472;year=2023;volume=13;issue=1;spage=106;epage=108;aulast=Malinovicaortic dissectioncase reportdilated aortahigh-risk pregnancymarfan syndrome
spellingShingle Matea Malinovic
Kimberly Babiash
Felecia Newton
Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report
Journal of Obstetric Anaesthesia and Critical Care
aortic dissection
case report
dilated aorta
high-risk pregnancy
marfan syndrome
title Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report
title_full Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report
title_fullStr Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report
title_full_unstemmed Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report
title_short Combined spinal-epidural anesthetic management of delivery for marfan syndrome: Case report
title_sort combined spinal epidural anesthetic management of delivery for marfan syndrome case report
topic aortic dissection
case report
dilated aorta
high-risk pregnancy
marfan syndrome
url http://www.joacc.com/article.asp?issn=2249-4472;year=2023;volume=13;issue=1;spage=106;epage=108;aulast=Malinovic
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AT kimberlybabiash combinedspinalepiduralanestheticmanagementofdeliveryformarfansyndromecasereport
AT felecianewton combinedspinalepiduralanestheticmanagementofdeliveryformarfansyndromecasereport