A MexR Mutation Which Confers Aztreonam Resistance to Pseudomonas aeruginosa

A MexR Mutation Which Confers Aztreonam Resistance to Pseudomonas aeruginosa

Therapy for Pseudomonas aeruginosa infections is hard due to its high natural and acquirable antibiotic resistance. After colonization in the hosts, P. aeruginosa commonly accumulates genomic mutations which confer them antibiotic resistance and better adaptations to the host environment. Decipherin...

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Bibliographic Details
Main Authors: Zhenzhen Ma, Congjuan Xu, Xinxin Zhang, Dan Wang, Xiaolei Pan, Huimin Liu, Guangbo Zhu, Fang Bai, Zhihui Cheng, Weihui Wu, Yongxin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-06-01
Series:Frontiers in Microbiology
Subjects:
Pseudomonas aeruginosa
aztreonam resistance
mexR
MexAB-OprM
mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2021.659808/full

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