Drug Safety and Suicidality Risk of Chronic Pain Medications
Chronic pain is one of the main leading causes of disability in the world at present. A variety in the symptomatology, intensity and duration of this phenomenon has led to an ever-increasing demand of pharmacological treatment and relief. This demand for medication, ranging from well-known groups, s...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-10-01
|
| Series: | Pharmaceuticals |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1424-8247/16/10/1497 |
| _version_ | 1797572643486957568 |
|---|---|
| author | Osman Syed Predrag Jancic Adam B. Fink Nebojsa Nick Knezevic |
| author_facet | Osman Syed Predrag Jancic Adam B. Fink Nebojsa Nick Knezevic |
| author_sort | Osman Syed |
| collection | DOAJ |
| description | Chronic pain is one of the main leading causes of disability in the world at present. A variety in the symptomatology, intensity and duration of this phenomenon has led to an ever-increasing demand of pharmacological treatment and relief. This demand for medication, ranging from well-known groups, such as antidepressants and benzodiazepines, to more novel drugs, was followed by a rise in safety concerns of such treatment options. The validity, frequency, and diversity of such concerns are discussed in this paper, as well as their possible effect on future prescription practices. A specific caution is provided towards the psychological safety and toll of these medications, regarding suicidality and suicidal ideation. Most significantly, this paper highlights the importance of pharmacovigilance and underscores the necessity of surveillance programs when considering chronic pain medication. |
| first_indexed | 2024-03-10T20:58:54Z |
| format | Article |
| id | doaj.art-9d3b637023774104b472adbeb1b477a6 |
| institution | Directory Open Access Journal |
| issn | 1424-8247 |
| language | English |
| last_indexed | 2024-03-10T20:58:54Z |
| publishDate | 2023-10-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceuticals |
| spelling | doaj.art-9d3b637023774104b472adbeb1b477a62023-11-19T17:43:21ZengMDPI AGPharmaceuticals1424-82472023-10-011610149710.3390/ph16101497Drug Safety and Suicidality Risk of Chronic Pain MedicationsOsman Syed0Predrag Jancic1Adam B. Fink2Nebojsa Nick Knezevic3Advocate Illinois Masonic Medical Center, Department of Anesthesiology, Chicago, IL 60657, USAAdvocate Illinois Masonic Medical Center, Department of Anesthesiology, Chicago, IL 60657, USAAdvocate Illinois Masonic Medical Center, Department of Anesthesiology, Chicago, IL 60657, USAAdvocate Illinois Masonic Medical Center, Department of Anesthesiology, Chicago, IL 60657, USAChronic pain is one of the main leading causes of disability in the world at present. A variety in the symptomatology, intensity and duration of this phenomenon has led to an ever-increasing demand of pharmacological treatment and relief. This demand for medication, ranging from well-known groups, such as antidepressants and benzodiazepines, to more novel drugs, was followed by a rise in safety concerns of such treatment options. The validity, frequency, and diversity of such concerns are discussed in this paper, as well as their possible effect on future prescription practices. A specific caution is provided towards the psychological safety and toll of these medications, regarding suicidality and suicidal ideation. Most significantly, this paper highlights the importance of pharmacovigilance and underscores the necessity of surveillance programs when considering chronic pain medication.https://www.mdpi.com/1424-8247/16/10/1497drug safetychronic painsuicidalityopioidsbenzodiazepinesantidepressants |
| spellingShingle | Osman Syed Predrag Jancic Adam B. Fink Nebojsa Nick Knezevic Drug Safety and Suicidality Risk of Chronic Pain Medications Pharmaceuticals drug safety chronic pain suicidality opioids benzodiazepines antidepressants |
| title | Drug Safety and Suicidality Risk of Chronic Pain Medications |
| title_full | Drug Safety and Suicidality Risk of Chronic Pain Medications |
| title_fullStr | Drug Safety and Suicidality Risk of Chronic Pain Medications |
| title_full_unstemmed | Drug Safety and Suicidality Risk of Chronic Pain Medications |
| title_short | Drug Safety and Suicidality Risk of Chronic Pain Medications |
| title_sort | drug safety and suicidality risk of chronic pain medications |
| topic | drug safety chronic pain suicidality opioids benzodiazepines antidepressants |
| url | https://www.mdpi.com/1424-8247/16/10/1497 |
| work_keys_str_mv | AT osmansyed drugsafetyandsuicidalityriskofchronicpainmedications AT predragjancic drugsafetyandsuicidalityriskofchronicpainmedications AT adambfink drugsafetyandsuicidalityriskofchronicpainmedications AT nebojsanickknezevic drugsafetyandsuicidalityriskofchronicpainmedications |