Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction
Objective We evaluated the safety and efficacy of rotational atherectomy (RA) in patients with a reduced left ventricular ejection fraction (LVEF). Methods In total, 140 consecutive patients with severe coronary artery calcification (CAC) who underwent RA were retrospectively enrolled. Patients were...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2020-10-01
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| Series: | Journal of International Medical Research |
| Online Access: | https://doi.org/10.1177/0300060519895144 |
| _version_ | 1819024191354044416 |
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| author | Hui-Ping Zhang Ying Zhao Hu Ai Hui Li Guo-Dong Tang Nai-Xin Zheng Fu-Cheng Sun |
| author_facet | Hui-Ping Zhang Ying Zhao Hu Ai Hui Li Guo-Dong Tang Nai-Xin Zheng Fu-Cheng Sun |
| author_sort | Hui-Ping Zhang |
| collection | DOAJ |
| description | Objective We evaluated the safety and efficacy of rotational atherectomy (RA) in patients with a reduced left ventricular ejection fraction (LVEF). Methods In total, 140 consecutive patients with severe coronary artery calcification (CAC) who underwent RA were retrospectively enrolled. Patients were grouped based on LVEF: ≤35% (n = 10), 36% to 50% (n = 11), and >50% (n = 119). We assessed procedural success and periprocedural complication rates as well as the incidences of in-hospital and 2-year major adverse cardiac events (MACEs), defined as hospitalization for myocardial infarction and worsening heart failure, target vessel revascularization, and cardiac death. Results Procedural success was achieved in nearly all patients in each group. Most periprocedural complications were minor, and major complications were uncommon. The 2-year MACE rate was significantly higher in the LVEF ≤35% than LVEF >50% group (40.0% vs. 6.7%, respectively). Multivariable regression analysis revealed that the LVEF was the only independent predictor of 2-year MACEs in patients who underwent RA. Conclusions Patients with a reduced LVEF who underwent RA had procedural success rates similar to those of patients with preserved left ventricular systolic function. The LVEF might be an independent predictor of 2-year MACEs in patients with severe CAC after percutaneous coronary intervention following RA. |
| first_indexed | 2024-12-21T04:50:52Z |
| format | Article |
| id | doaj.art-9d3becfc308d47629fd3e33e252590a5 |
| institution | Directory Open Access Journal |
| issn | 1473-2300 |
| language | English |
| last_indexed | 2024-12-21T04:50:52Z |
| publishDate | 2020-10-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Journal of International Medical Research |
| spelling | doaj.art-9d3becfc308d47629fd3e33e252590a52022-12-21T19:15:26ZengSAGE PublishingJournal of International Medical Research1473-23002020-10-014810.1177/0300060519895144Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fractionHui-Ping ZhangYing ZhaoHu AiHui LiGuo-Dong TangNai-Xin ZhengFu-Cheng SunObjective We evaluated the safety and efficacy of rotational atherectomy (RA) in patients with a reduced left ventricular ejection fraction (LVEF). Methods In total, 140 consecutive patients with severe coronary artery calcification (CAC) who underwent RA were retrospectively enrolled. Patients were grouped based on LVEF: ≤35% (n = 10), 36% to 50% (n = 11), and >50% (n = 119). We assessed procedural success and periprocedural complication rates as well as the incidences of in-hospital and 2-year major adverse cardiac events (MACEs), defined as hospitalization for myocardial infarction and worsening heart failure, target vessel revascularization, and cardiac death. Results Procedural success was achieved in nearly all patients in each group. Most periprocedural complications were minor, and major complications were uncommon. The 2-year MACE rate was significantly higher in the LVEF ≤35% than LVEF >50% group (40.0% vs. 6.7%, respectively). Multivariable regression analysis revealed that the LVEF was the only independent predictor of 2-year MACEs in patients who underwent RA. Conclusions Patients with a reduced LVEF who underwent RA had procedural success rates similar to those of patients with preserved left ventricular systolic function. The LVEF might be an independent predictor of 2-year MACEs in patients with severe CAC after percutaneous coronary intervention following RA.https://doi.org/10.1177/0300060519895144 |
| spellingShingle | Hui-Ping Zhang Ying Zhao Hu Ai Hui Li Guo-Dong Tang Nai-Xin Zheng Fu-Cheng Sun Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction Journal of International Medical Research |
| title | Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction |
| title_full | Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction |
| title_fullStr | Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction |
| title_full_unstemmed | Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction |
| title_short | Outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction |
| title_sort | outcomes of coronary rotational atherectomy in patients with reduced left ventricular ejection fraction |
| url | https://doi.org/10.1177/0300060519895144 |
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