Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)

A repeated light head injury causes dystrophic-destructive changes in the brain structure, which are more marked than changes, caused by primary head injury These changes are characterized by extensive affection of microcirculation system in all brain sections being studied. As about micr...

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Main Authors: A. T. Nosov, N. V. Kadjaya
Format: Article
Language:English
Published: Romodanov Neurosurgery Institute 2006-03-01
Series:Ukrainian Neurosurgical Journal
Online Access:https://theunj.org/article/view/126754
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author A. T. Nosov
N. V. Kadjaya
author_facet A. T. Nosov
N. V. Kadjaya
author_sort A. T. Nosov
collection DOAJ
description A repeated light head injury causes dystrophic-destructive changes in the brain structure, which are more marked than changes, caused by primary head injury These changes are characterized by extensive affection of microcirculation system in all brain sections being studied. As about microvessels, one month following a repeated head injury, endotheliocytes structure failure was observed, while capillary lumen expanded and erythrocytes statis and mural thrombosis occured.Changes in the cortex neurons in case of a repeated light head became stabilized only 60 days after the head injury, while changes in the synaptic system, although tending to restore, even 60 days after a repeated head injury were different from the control level.In case of a repeated head injury in all sections of the brain that were studied, and primarily in the area of the damaged hemisphere, gliosis prevailed and manifested itself in as increase of glial cells number mostly located in the areas of changed microvessels.
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spelling doaj.art-9d3c6189081c412c95efef8197cd4b0e2024-02-03T08:16:06ZengRomodanov Neurosurgery InstituteUkrainian Neurosurgical Journal2663-90842663-90922006-03-011919810.25305/unj.126754Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)A. T. Nosov0N. V. Kadjaya1Romodanov Neurosurgery Institute, Kiev, UkraineRomodanov Neurosurgery Institute, Kiev, Ukraine A repeated light head injury causes dystrophic-destructive changes in the brain structure, which are more marked than changes, caused by primary head injury These changes are characterized by extensive affection of microcirculation system in all brain sections being studied. As about microvessels, one month following a repeated head injury, endotheliocytes structure failure was observed, while capillary lumen expanded and erythrocytes statis and mural thrombosis occured.Changes in the cortex neurons in case of a repeated light head became stabilized only 60 days after the head injury, while changes in the synaptic system, although tending to restore, even 60 days after a repeated head injury were different from the control level.In case of a repeated head injury in all sections of the brain that were studied, and primarily in the area of the damaged hemisphere, gliosis prevailed and manifested itself in as increase of glial cells number mostly located in the areas of changed microvessels.https://theunj.org/article/view/126754
spellingShingle A. T. Nosov
N. V. Kadjaya
Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)
Ukrainian Neurosurgical Journal
title Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)
title_full Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)
title_fullStr Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)
title_full_unstemmed Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)
title_short Morfofunctional changes of the brain tissue after repeated mild brain injury (experimental research)
title_sort morfofunctional changes of the brain tissue after repeated mild brain injury experimental research
url https://theunj.org/article/view/126754
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