Multifunctional transition and temperature-responsive contact lenses
Abstract Smart contact lenses have recently gained traction due to their functionalization as noninvasive diagnostic and therapeutic wearables that can address several ocular diseases. Herein, multifunctional contact lenses exhibiting UV-transition and temperature-responsive capabilities were develo...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2023-11-01
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| Series: | Light: Science & Applications |
| Online Access: | https://doi.org/10.1038/s41377-023-01304-1 |
| _version_ | 1797556383974948864 |
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| author | Ahmed E. Salih Haider Butt |
| author_facet | Ahmed E. Salih Haider Butt |
| author_sort | Ahmed E. Salih |
| collection | DOAJ |
| description | Abstract Smart contact lenses have recently gained traction due to their functionalization as noninvasive diagnostic and therapeutic wearables that can address several ocular diseases. Herein, multifunctional contact lenses exhibiting UV-transition and temperature-responsive capabilities were developed utilizing chromogenic materials that were integrated simultaneously into poly(2-hydroxyethyl methacrylate) (pHEMA) contact lenses. The functionalities of the contact lenses were optically evaluated in both their activated and non-activated states. Transition contact lenses offered excellent UV and blue light blocking capabilities (~45%) at their inactive states. When activated via UV exposure, the transparent lenses darkened instantaneously and absorbed portions of the visible light spectrum. The absorption intensity and transient discoloration of the transition lenses relied primarily on the utilized photochromic material. Likewise, the temperature-responsive contact lenses exhibited distinct colorimetric variations in response to temperature changes within the physiological range (33–38 °C). The maximum sensitivity of the thermochromic lens was 8% transmitted light per Celsius degree shift. Physiochemical and morphological analysis indicated the adequacy of the contact lenses. Hence, the multifunctional contact lenses can be deployed as smart wearables to manage ophthalmic deficiencies that are deterred by UV radiations and variations in ocular surface temperature. |
| first_indexed | 2024-03-10T17:01:05Z |
| format | Article |
| id | doaj.art-9d40f601a9e84747a51d7bd06a2b1816 |
| institution | Directory Open Access Journal |
| issn | 2047-7538 |
| language | English |
| last_indexed | 2024-03-10T17:01:05Z |
| publishDate | 2023-11-01 |
| publisher | Nature Publishing Group |
| record_format | Article |
| series | Light: Science & Applications |
| spelling | doaj.art-9d40f601a9e84747a51d7bd06a2b18162023-11-20T10:58:20ZengNature Publishing GroupLight: Science & Applications2047-75382023-11-0112111210.1038/s41377-023-01304-1Multifunctional transition and temperature-responsive contact lensesAhmed E. Salih0Haider Butt1Department of Mechanical Engineering, Khalifa UniversityDepartment of Mechanical Engineering, Khalifa UniversityAbstract Smart contact lenses have recently gained traction due to their functionalization as noninvasive diagnostic and therapeutic wearables that can address several ocular diseases. Herein, multifunctional contact lenses exhibiting UV-transition and temperature-responsive capabilities were developed utilizing chromogenic materials that were integrated simultaneously into poly(2-hydroxyethyl methacrylate) (pHEMA) contact lenses. The functionalities of the contact lenses were optically evaluated in both their activated and non-activated states. Transition contact lenses offered excellent UV and blue light blocking capabilities (~45%) at their inactive states. When activated via UV exposure, the transparent lenses darkened instantaneously and absorbed portions of the visible light spectrum. The absorption intensity and transient discoloration of the transition lenses relied primarily on the utilized photochromic material. Likewise, the temperature-responsive contact lenses exhibited distinct colorimetric variations in response to temperature changes within the physiological range (33–38 °C). The maximum sensitivity of the thermochromic lens was 8% transmitted light per Celsius degree shift. Physiochemical and morphological analysis indicated the adequacy of the contact lenses. Hence, the multifunctional contact lenses can be deployed as smart wearables to manage ophthalmic deficiencies that are deterred by UV radiations and variations in ocular surface temperature.https://doi.org/10.1038/s41377-023-01304-1 |
| spellingShingle | Ahmed E. Salih Haider Butt Multifunctional transition and temperature-responsive contact lenses Light: Science & Applications |
| title | Multifunctional transition and temperature-responsive contact lenses |
| title_full | Multifunctional transition and temperature-responsive contact lenses |
| title_fullStr | Multifunctional transition and temperature-responsive contact lenses |
| title_full_unstemmed | Multifunctional transition and temperature-responsive contact lenses |
| title_short | Multifunctional transition and temperature-responsive contact lenses |
| title_sort | multifunctional transition and temperature responsive contact lenses |
| url | https://doi.org/10.1038/s41377-023-01304-1 |
| work_keys_str_mv | AT ahmedesalih multifunctionaltransitionandtemperatureresponsivecontactlenses AT haiderbutt multifunctionaltransitionandtemperatureresponsivecontactlenses |