Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report
Guillain-Barré syndrome (GBS) is an immune-mediated condition affecting both the motor and sensory spinal roots and peripheric nerves. GBS is a rare entity, with its global incidence being as low as 0.81 to 1.89 cases per 100.000 person-year. Despite its low incidence, GBS have an important morbidit...
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| Format: | Article |
| Language: | English |
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Asociación Colombiana de Infectología
2023-10-01
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| Series: | Infectio |
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| _version_ | 1797634087358300160 |
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| author | Diana Marcela Hoyos-Llanos |
| author_facet | Diana Marcela Hoyos-Llanos |
| author_sort | Diana Marcela Hoyos-Llanos |
| collection | DOAJ |
| description | Guillain-Barré syndrome (GBS) is an immune-mediated condition affecting both the motor and sensory spinal roots and peripheric nerves. GBS is a rare entity, with its global incidence being as low as 0.81 to 1.89 cases per 100.000 person-year. Despite its low incidence, GBS have an important morbidity and lethal potential. This syndrome is usually triggered by infections. Due to its clinical presentation heterogeneity and its disease natural history, there is scarse availability of international clinical practice guidelines for the management of this entity. In this report, we present the case of a 67 years-old man on his fifth month after liver transplant (LT), who developed acute non-inflammatory diarrhea followed by sudden ascending symmetric paresia and soles paresthesias. Electrophysiologic studies reported a demyelinating inflammatory polyradiculoneuropathy compatible with GBS, acute severe inflammatory demyelinating polyneuropathy (AIDP) subtype. His neurology deficit was associated with a simultaneous primary Cytomegalovirus (CMV) infection, one of the most common GBS-related infectious agents. |
| first_indexed | 2024-03-11T12:02:52Z |
| format | Article |
| id | doaj.art-9d411edf48414ad087007913db51b3ad |
| institution | Directory Open Access Journal |
| issn | 0123-9392 |
| language | English |
| last_indexed | 2024-03-11T12:02:52Z |
| publishDate | 2023-10-01 |
| publisher | Asociación Colombiana de Infectología |
| record_format | Article |
| series | Infectio |
| spelling | doaj.art-9d411edf48414ad087007913db51b3ad2023-11-07T21:22:32ZengAsociación Colombiana de InfectologíaInfectio0123-93922023-10-01273186190https://doi.org/10.22354/24223794.1144Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case reportDiana Marcela Hoyos-Llanos0https://orcid.org/0000-0001-9240-5547ransplant and Hepatology Services, Fundacion Santa Fe de Bogota University Hospital, Bogota, ColombiaGuillain-Barré syndrome (GBS) is an immune-mediated condition affecting both the motor and sensory spinal roots and peripheric nerves. GBS is a rare entity, with its global incidence being as low as 0.81 to 1.89 cases per 100.000 person-year. Despite its low incidence, GBS have an important morbidity and lethal potential. This syndrome is usually triggered by infections. Due to its clinical presentation heterogeneity and its disease natural history, there is scarse availability of international clinical practice guidelines for the management of this entity. In this report, we present the case of a 67 years-old man on his fifth month after liver transplant (LT), who developed acute non-inflammatory diarrhea followed by sudden ascending symmetric paresia and soles paresthesias. Electrophysiologic studies reported a demyelinating inflammatory polyradiculoneuropathy compatible with GBS, acute severe inflammatory demyelinating polyneuropathy (AIDP) subtype. His neurology deficit was associated with a simultaneous primary Cytomegalovirus (CMV) infection, one of the most common GBS-related infectious agents.guillain-barre syndromeliver transplantationcytomegalovirusimmunosuppression. |
| spellingShingle | Diana Marcela Hoyos-Llanos Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report Infectio guillain-barre syndrome liver transplantation cytomegalovirus immunosuppression. |
| title | Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report |
| title_full | Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report |
| title_fullStr | Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report |
| title_full_unstemmed | Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report |
| title_short | Cytomegalovirus-related Guillain-Barre syndrome in an adult liver transplant recipient: a case report |
| title_sort | cytomegalovirus related guillain barre syndrome in an adult liver transplant recipient a case report |
| topic | guillain-barre syndrome liver transplantation cytomegalovirus immunosuppression. |
| work_keys_str_mv | AT dianamarcelahoyosllanos cytomegalovirusrelatedguillainbarresyndromeinanadultlivertransplantrecipientacasereport |