Medical treatment of an unusual cerebral hydatid disease
Abstract Background Hydatid disease is a worldwide zoonosis produced by the larval stage of cestodes of the Echinococcus genus. Hydatid disease primarily involves the liver and lungs. The brain is involved in less than 2% of cases. Surgery has long been the only choice for the treatment, but chemoth...
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| Format: | Article |
| Language: | English |
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BMC
2018-01-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | http://link.springer.com/article/10.1186/s12879-017-2935-2 |
| _version_ | 1818063244325027840 |
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| author | Shu Chen Ning Li Feifei Yang Jiqin Wu Yuekai Hu Shenglei Yu Qi Chen Xuan Wang Xinyu Wang Yuanyuan Liu Jianming Zheng |
| author_facet | Shu Chen Ning Li Feifei Yang Jiqin Wu Yuekai Hu Shenglei Yu Qi Chen Xuan Wang Xinyu Wang Yuanyuan Liu Jianming Zheng |
| author_sort | Shu Chen |
| collection | DOAJ |
| description | Abstract Background Hydatid disease is a worldwide zoonosis produced by the larval stage of cestodes of the Echinococcus genus. Hydatid disease primarily involves the liver and lungs. The brain is involved in less than 2% of cases. Surgery has long been the only choice for the treatment, but chemotherapy has been successfully replaced surgery in some special cases. Case presentation We report a rare hydatid disease case which presented with multiple lesions in right frontal lobe, an uncommon site, and in the liver and lungs. A 28-year-old woman presented with 6 months history of recurrent convulsion. Cranial magnetic resonance imaging found multiple lesions in right frontal lobe, so she was hospitalized for surgical treatment and received sodium valproate by oral for controlling epilepsy. Before the operation, other lesions were found in the liver and lungs by computerized tomography scan. There were multiple pulmonary nodules near the pleura and large cyst in the liver. The pathology of liver showed that it may be a hydatid disease. Then, positive serum antibodies for echinococcus antigen further confirmed our diagnosis. Since her central nerve system was involved, she received four pills (800 mg, about 17 mg/kg/day) albendazole treatment for 18 months without operation. Her symptoms abated and a follow-up magnetic resonance imaging showed that the lesion had obviously diminished after treatment. She was recurrence free 2 years after we stopped albendazole treatment. Conclusions This case reveals an uncommon pattern of intracranial hydatid disease. Albendazole can be beneficial for some inoperable cerebral hydatid disease patients. |
| first_indexed | 2024-12-10T14:17:01Z |
| format | Article |
| id | doaj.art-9d44489afda64c43b38b98f076fc0093 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-10T14:17:01Z |
| publishDate | 2018-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-9d44489afda64c43b38b98f076fc00932022-12-22T01:45:19ZengBMCBMC Infectious Diseases1471-23342018-01-011811410.1186/s12879-017-2935-2Medical treatment of an unusual cerebral hydatid diseaseShu Chen0Ning Li1Feifei Yang2Jiqin Wu3Yuekai Hu4Shenglei Yu5Qi Chen6Xuan Wang7Xinyu Wang8Yuanyuan Liu9Jianming Zheng10Department of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityDepartment of infectious diseases, Huashan Hospital, Fudan UniversityAbstract Background Hydatid disease is a worldwide zoonosis produced by the larval stage of cestodes of the Echinococcus genus. Hydatid disease primarily involves the liver and lungs. The brain is involved in less than 2% of cases. Surgery has long been the only choice for the treatment, but chemotherapy has been successfully replaced surgery in some special cases. Case presentation We report a rare hydatid disease case which presented with multiple lesions in right frontal lobe, an uncommon site, and in the liver and lungs. A 28-year-old woman presented with 6 months history of recurrent convulsion. Cranial magnetic resonance imaging found multiple lesions in right frontal lobe, so she was hospitalized for surgical treatment and received sodium valproate by oral for controlling epilepsy. Before the operation, other lesions were found in the liver and lungs by computerized tomography scan. There were multiple pulmonary nodules near the pleura and large cyst in the liver. The pathology of liver showed that it may be a hydatid disease. Then, positive serum antibodies for echinococcus antigen further confirmed our diagnosis. Since her central nerve system was involved, she received four pills (800 mg, about 17 mg/kg/day) albendazole treatment for 18 months without operation. Her symptoms abated and a follow-up magnetic resonance imaging showed that the lesion had obviously diminished after treatment. She was recurrence free 2 years after we stopped albendazole treatment. Conclusions This case reveals an uncommon pattern of intracranial hydatid disease. Albendazole can be beneficial for some inoperable cerebral hydatid disease patients.http://link.springer.com/article/10.1186/s12879-017-2935-2Hydatid diseaseBrainAlbendazole |
| spellingShingle | Shu Chen Ning Li Feifei Yang Jiqin Wu Yuekai Hu Shenglei Yu Qi Chen Xuan Wang Xinyu Wang Yuanyuan Liu Jianming Zheng Medical treatment of an unusual cerebral hydatid disease BMC Infectious Diseases Hydatid disease Brain Albendazole |
| title | Medical treatment of an unusual cerebral hydatid disease |
| title_full | Medical treatment of an unusual cerebral hydatid disease |
| title_fullStr | Medical treatment of an unusual cerebral hydatid disease |
| title_full_unstemmed | Medical treatment of an unusual cerebral hydatid disease |
| title_short | Medical treatment of an unusual cerebral hydatid disease |
| title_sort | medical treatment of an unusual cerebral hydatid disease |
| topic | Hydatid disease Brain Albendazole |
| url | http://link.springer.com/article/10.1186/s12879-017-2935-2 |
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