Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes.

Blocking KCa3.1 channels increases tumor cell killing by a subpopulation of human natural killer lymphocytes.

Natural killer (NK) cells are large granular lymphocytes that participate in both innate and adaptive immune responses against tumors and pathogens. They are also involved in other conditions, including organ rejection, graft-versus-host disease, recurrent spontaneous abortions, and autoimmune disea...

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Bibliographic Details
Main Authors: Shyny Koshy, Danli Wu, Xueyou Hu, Rajeev B Tajhya, Redwan Huq, Fatima S Khan, Michael W Pennington, Heike Wulff, Patricia Yotnda, Christine Beeton
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3795664?pdf=render

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