HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons

HO-1 upregulation promotes mitophagy-dependent ferroptosis in PM2.5-exposed hippocampal neurons

Fine particulate matter (PM2.5) has been extensively implicated in the pathogenesis of neurodevelopmental disorders, but the underlying mechanism remains unclear. Recent studies have revealed that PM2.5 plays a role in regulating iron metabolism and redox homeostasis in the brain, which is closely a...

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Bibliographic Details
Main Authors: Xiaolan Li, Qin Ran, Xiang He, Dan Peng, Anying Xiong, Manling Jiang, Lei Zhang, Junyi Wang, Lingling Bai, Shengbin Liu, Shiyue Li, Baoqing Sun, Guoping Li
Format: Article
Language:English
Published: Elsevier 2024-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
PM2.5
HO-1
Ferroptosis
Mitophagy
Neurotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324003907

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