Boiogito, a Japanese Traditional Herbal Medicine, Inhibits the Osteoclast Differentiation and Proliferation in the Subchondral Bone of an In Vivo Knee Osteoarthritis Rat Model

Boiogito, a Japanese Traditional Herbal Medicine, Inhibits the Osteoclast Differentiation and Proliferation in the Subchondral Bone of an In Vivo Knee Osteoarthritis Rat Model

Boiogito (BO), a Japanese traditional herbal medicine, has been reported to prevent knee osteoarthritis (KOA) development in in vivo studies. In the early stage of KOA, osteoclasts proliferate in the subchondral bone. This study aimed to investigate the preventive effect of BO on osteoclast prolifer...

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Bibliographic Details
Main Authors: Taro Kimura, Takayuki Okumo, Hideshi Ikemoto, Naoki Adachi, Haruka Takemura, Midori Mochizuki, Kanako Izukashi, Koji Kanzaki, Masataka Sunagawa
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Applied Sciences
Subjects:
osteoarthritis
subchondral bone
osteoclast
Boiogito
Kampo medicine
Online Access:https://www.mdpi.com/2076-3417/12/22/11518

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