Is there a Role for Cyclophilin Inhibitors in the Management of Primary Biliary Cirrhosis?

Is there a Role for Cyclophilin Inhibitors in the Management of Primary Biliary Cirrhosis?

Autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC) are poorly understood autoimmune liver diseases. Immunosuppression is used to treat AIH and ursodeoxycholic acid is used to slow the progression of PBC. Nevertheless, a proportion of patients with both disorders progress to liver failure...

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Bibliographic Details
Main Authors: Andrew L. Mason, Aldo J. Montano-Loza, Shawn T. Wasilenko
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:Viruses
Subjects:
primary biliary cirrhosis
de novo autoimmune hepatitis
cyclosporine A, viral pathogenesis
Online Access:http://www.mdpi.com/1999-4915/5/2/423

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