Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases
Bee Venom (BV) has long been used in Korea to relieve pain symptoms and to treat inflammatory diseases, such as rheumatoid arthritis. The underlying mechanisms of the anti-inflammatory and analgesic actions of BV have been proved to some extent. Additionally, recent clinical and experimental studies...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-06-01
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| Series: | Toxins |
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| Online Access: | http://www.mdpi.com/2072-6651/7/7/2413 |
| _version_ | 1811304181415280640 |
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| author | Deok-Sang Hwang Sun Kwang Kim Hyunsu Bae |
| author_facet | Deok-Sang Hwang Sun Kwang Kim Hyunsu Bae |
| author_sort | Deok-Sang Hwang |
| collection | DOAJ |
| description | Bee Venom (BV) has long been used in Korea to relieve pain symptoms and to treat inflammatory diseases, such as rheumatoid arthritis. The underlying mechanisms of the anti-inflammatory and analgesic actions of BV have been proved to some extent. Additionally, recent clinical and experimental studies have demonstrated that BV and BV-derived active components are applicable to a wide range of immunological and neurodegenerative diseases, including autoimmune diseases and Parkinson’s disease. These effects of BV are known to be mediated by modulating immune cells in the periphery, and glial cells and neurons in the central nervous system. This review will introduce the scientific evidence of the therapeutic effects of BV and its components on several immunological and neurological diseases, and describe their detailed mechanisms involved in regulating various immune responses and pathological changes in glia and neurons. |
| first_indexed | 2024-04-13T08:02:36Z |
| format | Article |
| id | doaj.art-9d593bcb189b42d59251894352c57e23 |
| institution | Directory Open Access Journal |
| issn | 2072-6651 |
| language | English |
| last_indexed | 2024-04-13T08:02:36Z |
| publishDate | 2015-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Toxins |
| spelling | doaj.art-9d593bcb189b42d59251894352c57e232022-12-22T02:55:15ZengMDPI AGToxins2072-66512015-06-01772413242110.3390/toxins7072413toxins7072413Therapeutic Effects of Bee Venom on Immunological and Neurological DiseasesDeok-Sang Hwang0Sun Kwang Kim1Hyunsu Bae2Department of Korean Medicine Obstetrics and Gynecology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, KoreaDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, KoreaDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26 Kyungheedae-ro, Dongdaemun-gu, Seoul 130-701, KoreaBee Venom (BV) has long been used in Korea to relieve pain symptoms and to treat inflammatory diseases, such as rheumatoid arthritis. The underlying mechanisms of the anti-inflammatory and analgesic actions of BV have been proved to some extent. Additionally, recent clinical and experimental studies have demonstrated that BV and BV-derived active components are applicable to a wide range of immunological and neurodegenerative diseases, including autoimmune diseases and Parkinson’s disease. These effects of BV are known to be mediated by modulating immune cells in the periphery, and glial cells and neurons in the central nervous system. This review will introduce the scientific evidence of the therapeutic effects of BV and its components on several immunological and neurological diseases, and describe their detailed mechanisms involved in regulating various immune responses and pathological changes in glia and neurons.http://www.mdpi.com/2072-6651/7/7/2413Bee Venomimmunological diseasesneurological diseases |
| spellingShingle | Deok-Sang Hwang Sun Kwang Kim Hyunsu Bae Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases Toxins Bee Venom immunological diseases neurological diseases |
| title | Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases |
| title_full | Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases |
| title_fullStr | Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases |
| title_full_unstemmed | Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases |
| title_short | Therapeutic Effects of Bee Venom on Immunological and Neurological Diseases |
| title_sort | therapeutic effects of bee venom on immunological and neurological diseases |
| topic | Bee Venom immunological diseases neurological diseases |
| url | http://www.mdpi.com/2072-6651/7/7/2413 |
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