PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS

Abstract. Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the local immunity system in fema...

Full description

Bibliographic Details
Main Authors: O. A. Gizinger, I. I. Dolgushin
Format: Article
Language:Russian
Published: St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists 2014-07-01
Series:Медицинская иммунология
Subjects:
Online Access:https://www.mimmun.ru/mimmun/article/view/651
_version_ 1797198034719735808
author O. A. Gizinger
I. I. Dolgushin
author_facet O. A. Gizinger
I. I. Dolgushin
author_sort O. A. Gizinger
collection DOAJ
description Abstract. Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the local immunity system in females with urogenital trichomoniasis has been studied in comparison with these values in healthy females. It has been established that infected females have increased levels of IL-1α, IL-1β, RAIL-1, TNFα, IL-8, while IFN-γ concentration is decreased. The obtained results enable to get a deeper insight into the cytokine-mediated reactions in the local immunity system of genital tracts in case of trichomoniasis.
first_indexed 2024-03-08T05:49:57Z
format Article
id doaj.art-9d59d75f595448cbab9aa293613c18b5
institution Directory Open Access Journal
issn 1563-0625
2313-741X
language Russian
last_indexed 2024-04-24T06:53:27Z
publishDate 2014-07-01
publisher St. Petersburg branch of the Russian Association of Allergologists and Clinical Immunologists
record_format Article
series Медицинская иммунология
spelling doaj.art-9d59d75f595448cbab9aa293613c18b52024-04-22T13:07:39ZrusSt. Petersburg branch of the Russian Association of Allergologists and Clinical ImmunologistsМедицинская иммунология1563-06252313-741X2014-07-0175-660160410.15789/1563-0625-2005-5-6-601-604648PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASISO. A. Gizinger0I. I. Dolgushin1НИИ иммунологии Челябинской государственной медицинской академии МУЗ, Кожно–венерологический диспансер №1 , г.ЧелябинскНИИ иммунологии Челябинской государственной медицинской академии МУЗ, Кожно–венерологический диспансер №1 , г.ЧелябинскAbstract. Study results of vaginal secretion cytokine system in 25 patients with urogenital trichomoniasis are presented. Concentration of interleukins:IL-1α, IL-1β, RAIL-1, TNFa, IL-8, IFN-γ has been performed. The character of pro-inflammatory cytokines changes in the local immunity system in females with urogenital trichomoniasis has been studied in comparison with these values in healthy females. It has been established that infected females have increased levels of IL-1α, IL-1β, RAIL-1, TNFα, IL-8, while IFN-γ concentration is decreased. The obtained results enable to get a deeper insight into the cytokine-mediated reactions in the local immunity system of genital tracts in case of trichomoniasis.https://www.mimmun.ru/mimmun/article/view/651local immunity systemurogenital trichomoniasisvaginal secretioncytokines
spellingShingle O. A. Gizinger
I. I. Dolgushin
PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
Медицинская иммунология
local immunity system
urogenital trichomoniasis
vaginal secretion
cytokines
title PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_full PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_fullStr PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_full_unstemmed PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_short PROINFLAMMATORY CYTOKINES PROFILE IN WOMEN WITH GENITOURINARY TRICHOMONIASIS
title_sort proinflammatory cytokines profile in women with genitourinary trichomoniasis
topic local immunity system
urogenital trichomoniasis
vaginal secretion
cytokines
url https://www.mimmun.ru/mimmun/article/view/651
work_keys_str_mv AT oagizinger proinflammatorycytokinesprofileinwomenwithgenitourinarytrichomoniasis
AT iidolgushin proinflammatorycytokinesprofileinwomenwithgenitourinarytrichomoniasis