IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies
Diabetes mellitus is one of the foremost diseases in the modern era and diabetic nephropathy contributes to a major percentage of end-stage kidney disease. Although diabetic nephropathy is difficult to revert back, detection of nondiabetic renal disease (NDRD) is important to detect as most of them...
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2021-01-01
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| Series: | Journal of Family Medicine and Primary Care |
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| Online Access: | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2021;volume=10;issue=6;spage=2419;epage=2422;aulast=Lyngdoh |
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| author | Bifica Sofia Lyngdoh Pakesh Baishya Jaya Mishra Evarisalin Marbaniang Biswajit Dey |
| author_facet | Bifica Sofia Lyngdoh Pakesh Baishya Jaya Mishra Evarisalin Marbaniang Biswajit Dey |
| author_sort | Bifica Sofia Lyngdoh |
| collection | DOAJ |
| description | Diabetes mellitus is one of the foremost diseases in the modern era and diabetic nephropathy contributes to a major percentage of end-stage kidney disease. Although diabetic nephropathy is difficult to revert back, detection of nondiabetic renal disease (NDRD) is important to detect as most of them are treatable. We describe a case of a 62-year-old female with long-standing diabetes mellitus presenting with massive proteinuria and clinical features of nephrotic syndrome. The kidney biopsy showed class III diabetic nephropathy along with focal proliferative glomerulonephritis with crescent formations. The immunofluorescence study showed strong mesangial IgA deposition with the predominance of lambda stain. This confirmed the diagnosis of diabetic nephropathy with superimposed IgA nephropathy. We reviewed eight Indian studies herewith to demonstrate NDRD spectrum in the Indian diabetic scenario. |
| first_indexed | 2024-12-22T15:39:13Z |
| format | Article |
| id | doaj.art-9d59da86627e48d9bc6e926a63be94eb |
| institution | Directory Open Access Journal |
| issn | 2249-4863 |
| language | English |
| last_indexed | 2024-12-22T15:39:13Z |
| publishDate | 2021-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj.art-9d59da86627e48d9bc6e926a63be94eb2022-12-21T18:21:11ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632021-01-011062419242210.4103/jfmpc.jfmpc_1962_20IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studiesBifica Sofia LyngdohPakesh BaishyaJaya MishraEvarisalin MarbaniangBiswajit DeyDiabetes mellitus is one of the foremost diseases in the modern era and diabetic nephropathy contributes to a major percentage of end-stage kidney disease. Although diabetic nephropathy is difficult to revert back, detection of nondiabetic renal disease (NDRD) is important to detect as most of them are treatable. We describe a case of a 62-year-old female with long-standing diabetes mellitus presenting with massive proteinuria and clinical features of nephrotic syndrome. The kidney biopsy showed class III diabetic nephropathy along with focal proliferative glomerulonephritis with crescent formations. The immunofluorescence study showed strong mesangial IgA deposition with the predominance of lambda stain. This confirmed the diagnosis of diabetic nephropathy with superimposed IgA nephropathy. We reviewed eight Indian studies herewith to demonstrate NDRD spectrum in the Indian diabetic scenario.http://www.jfmpc.com/article.asp?issn=2249-4863;year=2021;volume=10;issue=6;spage=2419;epage=2422;aulast=Lyngdohdiabetic nephropathyimmunofluorescencerenal biopsy |
| spellingShingle | Bifica Sofia Lyngdoh Pakesh Baishya Jaya Mishra Evarisalin Marbaniang Biswajit Dey IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies Journal of Family Medicine and Primary Care diabetic nephropathy immunofluorescence renal biopsy |
| title | IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies |
| title_full | IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies |
| title_fullStr | IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies |
| title_full_unstemmed | IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies |
| title_short | IgA nephropathy superimposed on diabetic nephropathy: A case report with review of literature in eight Indian studies |
| title_sort | iga nephropathy superimposed on diabetic nephropathy a case report with review of literature in eight indian studies |
| topic | diabetic nephropathy immunofluorescence renal biopsy |
| url | http://www.jfmpc.com/article.asp?issn=2249-4863;year=2021;volume=10;issue=6;spage=2419;epage=2422;aulast=Lyngdoh |
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