PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation

PEARLS – A multicentre phase II/III trial of extended field radiotherapy for androgen sensitive prostate cancer patients with PSMA‐avid pelvic and/or para-aortic lymph nodes at presentation

PEARLS is a multi-stage randomised controlled trial for prostate cancer patients with pelvic and/or para-aortic PSMA-avid lymph node disease at presentation. The aim of the trial is to determine whether extending the radiotherapy field to cover the para-aortic lymph nodes (up to L1/L2 vertebral inte...

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Bibliographic Details
Main Authors: Julia Murray, Clare Cruickshank, Thomas Bird, Philip Bell, John Braun, Dave Chuter, Miguel Reis Ferreira, Clare Griffin, Shama Hassan, Nabil Hujairi, Alan Melcher, Elizabeth Miles, Olivia Naismith, Miguel Panades, Lara Philipps, Alison Reid, Jan Rekowski, Pete Sankey, John Staffurth, Isabel Syndikus, Alison Tree, Anna Wilkins, Emma Hall
Format: Article
Language:English
Published: Elsevier 2022-11-01
Series:Clinical and Translational Radiation Oncology
Subjects:
Prostate
IMRT
Para-aortic lymph nodes
Randomized controlled trial
PSMA-PET
Online Access:http://www.sciencedirect.com/science/article/pii/S2405630822000787

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