Hierarchically Assembled Nanofiber Scaffolds with Dual Growth Factor Gradients Promote Skin Wound Healing Through Rapid Cell Recruitment

Hierarchically Assembled Nanofiber Scaffolds with Dual Growth Factor Gradients Promote Skin Wound Healing Through Rapid Cell Recruitment

Abstract To address current challenges in effectively treating large skin defects caused by trauma in clinical medicine, the fabrication, and evaluation of a novel radially aligned nanofiber scaffold (RAS) with dual growth factor gradients is presented. These aligned nanofibers and the scaffold'...

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Bibliographic Details
Main Authors: Ruyi Fan, Chuwei Zhang, Fei Li, Bo Li, Alec McCarthy, Yi Zhang, Shixuan Chen, Lin Zhang
Format: Article
Language:English
Published: Wiley 2024-04-01
Series:Advanced Science
Subjects:
cell recruitment
dual gradients
growth factors
radially aligned nanofiber scaffold
skin wound healing
Online Access:https://doi.org/10.1002/advs.202309993

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