Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy
Context: Disturbances in sleep affects the overall quality of a child's life, with several short- and long-lasting consequences. Hence, early diagnosis and monitoring is crucial in the management of sleep disorders in children. Aims: The aim of this study was to evaluate salivary C-reactive pro...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Indian Society of Pedodontics and Preventive Dentistry |
| Subjects: | |
| Online Access: | http://www.jisppd.com/article.asp?issn=0970-4388;year=2023;volume=41;issue=3;spage=190;epage=196;aulast=Bhosale |
| _version_ | 1827293228506808320 |
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| author | Trupti B Bhosale Vabitha Shetty Meghna Bhandary Prajna P Nayak |
| author_facet | Trupti B Bhosale Vabitha Shetty Meghna Bhandary Prajna P Nayak |
| author_sort | Trupti B Bhosale |
| collection | DOAJ |
| description | Context: Disturbances in sleep affects the overall quality of a child's life, with several short- and long-lasting consequences. Hence, early diagnosis and monitoring is crucial in the management of sleep disorders in children. Aims: The aim of this study was to evaluate salivary C-reactive protein (CRP) levels in a group of children with Class II malocclusion and sleep problems before and after twin-block appliance therapy. Settings and Design: The study was a prospective clinical study with a 9-month follow-up period. Subjects and Methods: Eleven children aged 8–12 years with skeletal Class II malocclusion and at least one sleep disorder were enrolled in the study. All children were subjected to a recording of their sleep history and a clinical as well as radiographic examination. Pretreatment levels of salivary CRP were recorded. A twin-block appliance was custom made and delivered to every child. At the end of 9-month follow-up, all children were recalled for a re-evaluation of salivary biomarker levels. Statistical Analysis: Pretreatment and posttreatment changes in biomarker levels were assessed statistically using the students paired t-test. Results: Levels of salivary biomarker CRP were significantly decreased in children following myofunctional therapy using a twin-block appliance (P < 0.001). There was a considerable improvement in the clinical symptoms such as a decrease in snoring and noisy breathing in most children post-twin-block therapy. Conclusion: The measurement of salivary biomarker CRP could be used as an alternative and noninvasive method to evaluate prognosis of oral myofunctional therapy for children with sleep disordered breathing. |
| first_indexed | 2024-04-24T13:21:43Z |
| format | Article |
| id | doaj.art-9d5df805aada481ea857e982cb88913e |
| institution | Directory Open Access Journal |
| issn | 0970-4388 1998-3905 |
| language | English |
| last_indexed | 2024-04-24T13:21:43Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Indian Society of Pedodontics and Preventive Dentistry |
| spelling | doaj.art-9d5df805aada481ea857e982cb88913e2024-04-04T14:36:58ZengWolters Kluwer Medknow PublicationsJournal of Indian Society of Pedodontics and Preventive Dentistry0970-43881998-39052023-01-0141319019610.4103/jisppd.jisppd_338_23Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapyTrupti B BhosaleVabitha ShettyMeghna BhandaryPrajna P NayakContext: Disturbances in sleep affects the overall quality of a child's life, with several short- and long-lasting consequences. Hence, early diagnosis and monitoring is crucial in the management of sleep disorders in children. Aims: The aim of this study was to evaluate salivary C-reactive protein (CRP) levels in a group of children with Class II malocclusion and sleep problems before and after twin-block appliance therapy. Settings and Design: The study was a prospective clinical study with a 9-month follow-up period. Subjects and Methods: Eleven children aged 8–12 years with skeletal Class II malocclusion and at least one sleep disorder were enrolled in the study. All children were subjected to a recording of their sleep history and a clinical as well as radiographic examination. Pretreatment levels of salivary CRP were recorded. A twin-block appliance was custom made and delivered to every child. At the end of 9-month follow-up, all children were recalled for a re-evaluation of salivary biomarker levels. Statistical Analysis: Pretreatment and posttreatment changes in biomarker levels were assessed statistically using the students paired t-test. Results: Levels of salivary biomarker CRP were significantly decreased in children following myofunctional therapy using a twin-block appliance (P < 0.001). There was a considerable improvement in the clinical symptoms such as a decrease in snoring and noisy breathing in most children post-twin-block therapy. Conclusion: The measurement of salivary biomarker CRP could be used as an alternative and noninvasive method to evaluate prognosis of oral myofunctional therapy for children with sleep disordered breathing.http://www.jisppd.com/article.asp?issn=0970-4388;year=2023;volume=41;issue=3;spage=190;epage=196;aulast=Bhosalebiomarkersc-reactive proteinmyofunctional therapyobstructive sleep apneasaliva |
| spellingShingle | Trupti B Bhosale Vabitha Shetty Meghna Bhandary Prajna P Nayak Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy Journal of Indian Society of Pedodontics and Preventive Dentistry biomarkers c-reactive protein myofunctional therapy obstructive sleep apnea saliva |
| title | Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy |
| title_full | Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy |
| title_fullStr | Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy |
| title_full_unstemmed | Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy |
| title_short | Salivary biomarker C-reactive protein levels in children with sleep problems and Class II malocclusion before and after twin-block therapy |
| title_sort | salivary biomarker c reactive protein levels in children with sleep problems and class ii malocclusion before and after twin block therapy |
| topic | biomarkers c-reactive protein myofunctional therapy obstructive sleep apnea saliva |
| url | http://www.jisppd.com/article.asp?issn=0970-4388;year=2023;volume=41;issue=3;spage=190;epage=196;aulast=Bhosale |
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