TOM40 regulates the progression of nasopharyngeal carcinoma through ROS-mediated AKT/mTOR and p53 signaling

TOM40 regulates the progression of nasopharyngeal carcinoma through ROS-mediated AKT/mTOR and p53 signaling

Abstract Nasopharyngeal carcinoma (NPC) is a prevalent cancer in Southern China, North Africa, and Southeast Asia. The translocase of the outer membrane (TOM) 40 is a transporter of mitochondrial proteins, and is involved in ovarian cancer cell growth. However, its role in the progression of NPC is...

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Bibliographic Details
Main Authors: Hong Ran, Jin Zhang, Xiaoxia Zeng, Zhen Wang, Peng Liu, Chenglin Kang, Shuqi Qiu, Xianhai Zeng, Peng Zhang
Format: Article
Language:English
Published: Springer 2023-06-01
Series:Discover Oncology
Subjects:
Nasopharyngeal carcinoma
TOM40
ROS
AKT
p53
Online Access:https://doi.org/10.1007/s12672-023-00721-3

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