Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases
Kidney diseases are regarded as one of the major public health issues in the world. The objectives of this study were: (i) to investigate the causative factors involved in kidney disease and the therapeutic aspects of <i>Moringa oleifera</i>, as well as (ii) the effectiveness of <i>...
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| Format: | Article |
| Language: | English |
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MDPI AG
2021-12-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/10/12/2818 |
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| author | Tanzina Akter Md Atikur Rahman Akhi Moni Md. Aminul Islam Apu Atqiya Fariha Md. Abdul Hannan Md Jamal Uddin |
| author_facet | Tanzina Akter Md Atikur Rahman Akhi Moni Md. Aminul Islam Apu Atqiya Fariha Md. Abdul Hannan Md Jamal Uddin |
| author_sort | Tanzina Akter |
| collection | DOAJ |
| description | Kidney diseases are regarded as one of the major public health issues in the world. The objectives of this study were: (i) to investigate the causative factors involved in kidney disease and the therapeutic aspects of <i>Moringa oleifera</i>, as well as (ii) the effectiveness of <i>M. oleifera</i> in the anti-inflammation and antioxidant processes of the kidney while minimizing all potential side effects. In addition, we proposed a hypothesis to improve <i>M. oleifera</i> based drug development. This study was updated by searching the key words <i>M. oleifera</i> on kidney diseases and <i>M. oleifera</i> on oxidative stress, inflammation, and fibrosis in online research databases such as PubMed and Google Scholar. The following validation checking and scrutiny analysis of the recently published articles were used to explore this study. The recent existing research has found that <i>M. oleifera</i> has a plethora of health benefits. Individual medicinal properties of <i>M. oleifera</i> leaf extract, seed powder, stem extract, and the whole extract (ethanol/methanol) can up-increase the activity of antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH), while decreasing the activity of inflammatory cytokines such as TNF-α, IL-1β, IL-6, and COX-2. In our study, we have investigated the properties of this plant against kidney diseases based on existing knowledge with an updated review of literature. Considering the effectiveness of <i>M. oleifera</i>, this study would be useful for further research into the pharmacological potential and therapeutic insights of <i>M. oleifera</i>, as well as prospects of <i>Moringa</i>-based effective medicine development for human benefits. |
| first_indexed | 2024-03-10T03:16:42Z |
| format | Article |
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| institution | Directory Open Access Journal |
| issn | 2223-7747 |
| language | English |
| last_indexed | 2024-03-10T03:16:42Z |
| publishDate | 2021-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj.art-9d5eba7e546c4a568458d4a6a3f2bacd2023-11-23T10:13:40ZengMDPI AGPlants2223-77472021-12-011012281810.3390/plants10122818Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney DiseasesTanzina Akter0Md Atikur Rahman1Akhi Moni2Md. Aminul Islam Apu3Atqiya Fariha4Md. Abdul Hannan5Md Jamal Uddin6ABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshABEx Bio-Research Center, East Azampur, Dhaka 1230, BangladeshKidney diseases are regarded as one of the major public health issues in the world. The objectives of this study were: (i) to investigate the causative factors involved in kidney disease and the therapeutic aspects of <i>Moringa oleifera</i>, as well as (ii) the effectiveness of <i>M. oleifera</i> in the anti-inflammation and antioxidant processes of the kidney while minimizing all potential side effects. In addition, we proposed a hypothesis to improve <i>M. oleifera</i> based drug development. This study was updated by searching the key words <i>M. oleifera</i> on kidney diseases and <i>M. oleifera</i> on oxidative stress, inflammation, and fibrosis in online research databases such as PubMed and Google Scholar. The following validation checking and scrutiny analysis of the recently published articles were used to explore this study. The recent existing research has found that <i>M. oleifera</i> has a plethora of health benefits. Individual medicinal properties of <i>M. oleifera</i> leaf extract, seed powder, stem extract, and the whole extract (ethanol/methanol) can up-increase the activity of antioxidant enzymes like superoxide dismutase (SOD), catalase (CAT), and glutathione (GSH), while decreasing the activity of inflammatory cytokines such as TNF-α, IL-1β, IL-6, and COX-2. In our study, we have investigated the properties of this plant against kidney diseases based on existing knowledge with an updated review of literature. Considering the effectiveness of <i>M. oleifera</i>, this study would be useful for further research into the pharmacological potential and therapeutic insights of <i>M. oleifera</i>, as well as prospects of <i>Moringa</i>-based effective medicine development for human benefits.https://www.mdpi.com/2223-7747/10/12/2818<i>Moringa oleifera</i>antioxidantanti-agingfibrosisinflammationkidney disease |
| spellingShingle | Tanzina Akter Md Atikur Rahman Akhi Moni Md. Aminul Islam Apu Atqiya Fariha Md. Abdul Hannan Md Jamal Uddin Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases Plants <i>Moringa oleifera</i> antioxidant anti-aging fibrosis inflammation kidney disease |
| title | Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases |
| title_full | Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases |
| title_fullStr | Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases |
| title_full_unstemmed | Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases |
| title_short | Prospects for Protective Potential of <i>Moringa oleifera</i> against Kidney Diseases |
| title_sort | prospects for protective potential of i moringa oleifera i against kidney diseases |
| topic | <i>Moringa oleifera</i> antioxidant anti-aging fibrosis inflammation kidney disease |
| url | https://www.mdpi.com/2223-7747/10/12/2818 |
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