Artificial Tear Instillation-Induced Changes in Corneal Topography
This study aims to compare changes of corneal topography (Galilei G4) before and after the instillation of artificial tears in patients with dry eye disease (DED). Corneal topography was performed in patients 1 min before and after artificial tear instillation. Two types of artificial tears were use...
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MDPI AG
2024-01-01
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| Series: | Bioengineering |
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| Online Access: | https://www.mdpi.com/2306-5354/11/2/121 |
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| author | Yunjin Lee Tae Hun Kim Hae Jung Paik Dong Hyun Kim |
| author_facet | Yunjin Lee Tae Hun Kim Hae Jung Paik Dong Hyun Kim |
| author_sort | Yunjin Lee |
| collection | DOAJ |
| description | This study aims to compare changes of corneal topography (Galilei G4) before and after the instillation of artificial tears in patients with dry eye disease (DED). Corneal topography was performed in patients 1 min before and after artificial tear instillation. Two types of artificial tears were used: 1% polysorbate 80 (PSB) and 0.5% carboxymethylcellulose (CMC). Of 135 patients, PSB and CMC were instilled in 101 and 34 eyes, respectively. The average value of Sim K increased significantly after instillation (44.07 ± 2.26 diopter (D)) compared to before (43.90 ± 2.02 D, <i>p</i> = 0.006) the instillation of artificial tears. Mean Sim K astigmatism was statistically increased after PSB instillation (1.48 ± 2.17 D) compared to before instillation (1.31 ± 2.10 D, <i>p</i> = 0.049). An axis change of astigmatism 10° or more after artificial tear instillation was found in 51.9% of patients, and 30° or more in 20.0% of patients. Increased Sim K value and significant changes in the astigmatic axis in the corneal topography were observed after instillation of artificial tears in DED patients. PSB instillation had a greater effect on corneal keratometry values than CMC instillation. |
| first_indexed | 2024-03-07T22:41:51Z |
| format | Article |
| id | doaj.art-9d603fa8134945a98b20f0ebe5b3b250 |
| institution | Directory Open Access Journal |
| issn | 2306-5354 |
| language | English |
| last_indexed | 2024-03-07T22:41:51Z |
| publishDate | 2024-01-01 |
| publisher | MDPI AG |
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| series | Bioengineering |
| spelling | doaj.art-9d603fa8134945a98b20f0ebe5b3b2502024-02-23T15:07:52ZengMDPI AGBioengineering2306-53542024-01-0111212110.3390/bioengineering11020121Artificial Tear Instillation-Induced Changes in Corneal TopographyYunjin Lee0Tae Hun Kim1Hae Jung Paik2Dong Hyun Kim3Department of Ophthalmology, Gachon University College of Medicine, Gil Medical Center, 21, Namdong-daero 774beon-gil, Namdong-gu, Incheon 21565, Republic of KoreaDepartment of Ophthalmology, Gachon University College of Medicine, Gil Medical Center, 21, Namdong-daero 774beon-gil, Namdong-gu, Incheon 21565, Republic of KoreaDepartment of Ophthalmology, Gachon University College of Medicine, Gil Medical Center, 21, Namdong-daero 774beon-gil, Namdong-gu, Incheon 21565, Republic of KoreaDepartment of Ophthalmology, Korea University College of Medicine, 73, Goryeodae-ro, Seongbuk-gu, Seoul 02841, Republic of KoreaThis study aims to compare changes of corneal topography (Galilei G4) before and after the instillation of artificial tears in patients with dry eye disease (DED). Corneal topography was performed in patients 1 min before and after artificial tear instillation. Two types of artificial tears were used: 1% polysorbate 80 (PSB) and 0.5% carboxymethylcellulose (CMC). Of 135 patients, PSB and CMC were instilled in 101 and 34 eyes, respectively. The average value of Sim K increased significantly after instillation (44.07 ± 2.26 diopter (D)) compared to before (43.90 ± 2.02 D, <i>p</i> = 0.006) the instillation of artificial tears. Mean Sim K astigmatism was statistically increased after PSB instillation (1.48 ± 2.17 D) compared to before instillation (1.31 ± 2.10 D, <i>p</i> = 0.049). An axis change of astigmatism 10° or more after artificial tear instillation was found in 51.9% of patients, and 30° or more in 20.0% of patients. Increased Sim K value and significant changes in the astigmatic axis in the corneal topography were observed after instillation of artificial tears in DED patients. PSB instillation had a greater effect on corneal keratometry values than CMC instillation.https://www.mdpi.com/2306-5354/11/2/121corneal topographykeratometryastigmatismartificial tear |
| spellingShingle | Yunjin Lee Tae Hun Kim Hae Jung Paik Dong Hyun Kim Artificial Tear Instillation-Induced Changes in Corneal Topography Bioengineering corneal topography keratometry astigmatism artificial tear |
| title | Artificial Tear Instillation-Induced Changes in Corneal Topography |
| title_full | Artificial Tear Instillation-Induced Changes in Corneal Topography |
| title_fullStr | Artificial Tear Instillation-Induced Changes in Corneal Topography |
| title_full_unstemmed | Artificial Tear Instillation-Induced Changes in Corneal Topography |
| title_short | Artificial Tear Instillation-Induced Changes in Corneal Topography |
| title_sort | artificial tear instillation induced changes in corneal topography |
| topic | corneal topography keratometry astigmatism artificial tear |
| url | https://www.mdpi.com/2306-5354/11/2/121 |
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