Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis
Depression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients livi...
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2021-10-01
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author | Yoann Birling Sarah Nevitt Deep Jyoti Bhuyan Mingxian Jia Fan Feng Linda Ellen Carlson Tiffany Pham Jing Liu Zahra Ayati Liyi Nyiam Zhichao Yu Paul Fahey |
author_facet | Yoann Birling Sarah Nevitt Deep Jyoti Bhuyan Mingxian Jia Fan Feng Linda Ellen Carlson Tiffany Pham Jing Liu Zahra Ayati Liyi Nyiam Zhichao Yu Paul Fahey |
author_sort | Yoann Birling |
collection | DOAJ |
description | Depression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients living with depression, anxiety, or insomnia. EMBase, PubMed, Cinahl, PsychINFO, IndMED, CSI-NISCAIR, CNKI, Clinicaltrial.gov, ChiCTR, and CTRI will be searched until October 2020 for relevant studies. Randomized controlled studies in which MBTs were tested in a cancer population will be selected. The authors of the selected studies will be contacted to obtain individual participant data. The participants who reached a defined clinical threshold for depression, anxiety, or insomnia will be selected for the three sub-studies on depression, anxiety, and insomnia, respectively. Pairwise and network meta-analyses will be used to assess the changes in depression, anxiety, sleep quality, and completion rate. We will assess the effect of the treatment dose (number and frequency of interventions) on effectiveness. The results of this study will inform clinical decision-making for the treatment of psychological disturbances in cancer patients. If MBTs are found effective, they will potentially be recommended as treatments for cancer patients with psychological symptoms. |
first_indexed | 2024-03-10T03:27:30Z |
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id | doaj.art-9d65a68868d44c9bb65679709fd2654c |
institution | Directory Open Access Journal |
issn | 2409-9279 |
language | English |
last_indexed | 2024-03-10T03:27:30Z |
publishDate | 2021-10-01 |
publisher | MDPI AG |
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series | Methods and Protocols |
spelling | doaj.art-9d65a68868d44c9bb65679709fd2654c2023-11-23T09:48:17ZengMDPI AGMethods and Protocols2409-92792021-10-01447610.3390/mps4040076Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-AnalysisYoann Birling0Sarah Nevitt1Deep Jyoti Bhuyan2Mingxian Jia3Fan Feng4Linda Ellen Carlson5Tiffany Pham6Jing Liu7Zahra Ayati8Liyi Nyiam9Zhichao Yu10Paul Fahey11NICM Health Research Institute, Western Sydney University, Penrith 2751, AustraliaInstitute of Population Health, University of Liverpool, Liverpool L69 3GF, UKNICM Health Research Institute, Western Sydney University, Penrith 2751, AustraliaInstitute of Chinese Medicine, China Resources Sanjiu Medical and Pharmaceutical Co., Ltd., Shenzhen 518110, ChinaBenson Henry Institute for Mind Body Medicine, Massachusetts General Hospital, Boston, MA 02114, USADepartment of Psychology, University of Calgary, Calgary, AB T2N 1N4, CanadaSchool of Health Sciences, Western Sydney University, Penrith 2751, AustraliaSchool of Health Sciences, Western Sydney University, Penrith 2751, AustraliaNICM Health Research Institute, Western Sydney University, Penrith 2751, AustraliaPre-Disease Treatment Department, The Gulou Hospital of Traditional Chinese Medicine of Beijing, Beijing 100009, ChinaSchool of Health Sciences, Western Sydney University, Penrith 2751, AustraliaSchool of Health Sciences, Western Sydney University, Penrith 2751, AustraliaDepression, anxiety, and insomnia are common in cancer patients. Mind-body therapies (MBTs) are promising forms of treatment for cancer patients living with depression, anxiety, and insomnia. The objective of this study is to assess the effectiveness and acceptability of MBTs in cancer patients living with depression, anxiety, or insomnia. EMBase, PubMed, Cinahl, PsychINFO, IndMED, CSI-NISCAIR, CNKI, Clinicaltrial.gov, ChiCTR, and CTRI will be searched until October 2020 for relevant studies. Randomized controlled studies in which MBTs were tested in a cancer population will be selected. The authors of the selected studies will be contacted to obtain individual participant data. The participants who reached a defined clinical threshold for depression, anxiety, or insomnia will be selected for the three sub-studies on depression, anxiety, and insomnia, respectively. Pairwise and network meta-analyses will be used to assess the changes in depression, anxiety, sleep quality, and completion rate. We will assess the effect of the treatment dose (number and frequency of interventions) on effectiveness. The results of this study will inform clinical decision-making for the treatment of psychological disturbances in cancer patients. If MBTs are found effective, they will potentially be recommended as treatments for cancer patients with psychological symptoms.https://www.mdpi.com/2409-9279/4/4/76cancerdepressionanxietyinsomniayogatai chi |
spellingShingle | Yoann Birling Sarah Nevitt Deep Jyoti Bhuyan Mingxian Jia Fan Feng Linda Ellen Carlson Tiffany Pham Jing Liu Zahra Ayati Liyi Nyiam Zhichao Yu Paul Fahey Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis Methods and Protocols cancer depression anxiety insomnia yoga tai chi |
title | Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis |
title_full | Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis |
title_fullStr | Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis |
title_full_unstemmed | Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis |
title_short | Mind-Body Therapies for Cancer Patients Living with Depression, Anxiety or Insomnia (MIRACLE): A Systematic Review with Individual Participant Data Network Meta-Analysis |
title_sort | mind body therapies for cancer patients living with depression anxiety or insomnia miracle a systematic review with individual participant data network meta analysis |
topic | cancer depression anxiety insomnia yoga tai chi |
url | https://www.mdpi.com/2409-9279/4/4/76 |
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