Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor

Targeting the Oncogenic Long Non-coding RNA SLNCR1 by Blocking Its Sequence-Specific Binding to the Androgen Receptor

Summary: Long non-coding RNAs (lncRNAs) are critical regulators of numerous physiological processes and diseases, especially cancers. However, development of lncRNA-based therapies is limited because the mechanisms of many lncRNAs are obscure, and interactions with functional partners, including pro...

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Bibliographic Details
Main Authors: Karyn Schmidt, Chase A. Weidmann, Thomas A. Hilimire, Elaine Yee, Breanne M. Hatfield, John S. Schneekloth, Jr., Kevin M. Weeks, Carl D. Novina
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471931650X

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