Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities

<i>Arbutus unedo</i>, commonly named ‘strawberry tree’ (ST), is a Mediterranean native plant that represents a relevant source of biologically active fractions and compounds. ST fruits, traditionally used with culinary and medicinal purposes, along with other components (leaves, roots, h...

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Main Author: Diego Morales
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Foods
Subjects:
Online Access:https://www.mdpi.com/2304-8158/11/23/3838
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author Diego Morales
author_facet Diego Morales
author_sort Diego Morales
collection DOAJ
description <i>Arbutus unedo</i>, commonly named ‘strawberry tree’ (ST), is a Mediterranean native plant that represents a relevant source of biologically active fractions and compounds. ST fruits, traditionally used with culinary and medicinal purposes, along with other components (leaves, roots, honeys, etc.), have been subjected to varied extraction procedures to obtain enriched and bioactive products. This work reviewed the scientific literature, searching for studies that evaluated the potential health implications of ST fractions and attending to the tested biological activities (antioxidant, antiproliferative, hypoglycemic, immune-modulatory, antihypertensive, antimicrobial, etc.), the part of the tree, the experimental model, the specific bioactive compounds and the selected extraction protocol. Furthermore, the strengths and weaknesses of the current state of the published evidence were critically analysed. Although in vitro results demonstrated the potential of ST fractions, further research is encouraged in order to obtain in vivo evidence (animal and clinical studies), assess additional activities (hypocholesterolemic, microbiome-modulatory), maximize the use of advanced extraction technologies, purify and isolate specific bioactive compounds and broaden the analysis investigating phenolic and non-phenolic molecules and their bioavailability.
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spelling doaj.art-9d6cb2b8908043cb97a8142b4bc99b232023-11-24T10:59:25ZengMDPI AGFoods2304-81582022-11-011123383810.3390/foods11233838Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological ActivitiesDiego Morales0Nutrigenomics Research Group, Department of Biochemistry and Biotechnology, Universitat Rovira i Virgili, 43007 Tarragona, Spain<i>Arbutus unedo</i>, commonly named ‘strawberry tree’ (ST), is a Mediterranean native plant that represents a relevant source of biologically active fractions and compounds. ST fruits, traditionally used with culinary and medicinal purposes, along with other components (leaves, roots, honeys, etc.), have been subjected to varied extraction procedures to obtain enriched and bioactive products. This work reviewed the scientific literature, searching for studies that evaluated the potential health implications of ST fractions and attending to the tested biological activities (antioxidant, antiproliferative, hypoglycemic, immune-modulatory, antihypertensive, antimicrobial, etc.), the part of the tree, the experimental model, the specific bioactive compounds and the selected extraction protocol. Furthermore, the strengths and weaknesses of the current state of the published evidence were critically analysed. Although in vitro results demonstrated the potential of ST fractions, further research is encouraged in order to obtain in vivo evidence (animal and clinical studies), assess additional activities (hypocholesterolemic, microbiome-modulatory), maximize the use of advanced extraction technologies, purify and isolate specific bioactive compounds and broaden the analysis investigating phenolic and non-phenolic molecules and their bioavailability.https://www.mdpi.com/2304-8158/11/23/3838<i>Arbutus unedo</i>strawberry treeantioxidantphenolic compoundsarbutinantitumoral
spellingShingle Diego Morales
Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities
Foods
<i>Arbutus unedo</i>
strawberry tree
antioxidant
phenolic compounds
arbutin
antitumoral
title Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities
title_full Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities
title_fullStr Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities
title_full_unstemmed Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities
title_short Use of Strawberry Tree (<i>Arbutus unedo</i>) as a Source of Functional Fractions with Biological Activities
title_sort use of strawberry tree i arbutus unedo i as a source of functional fractions with biological activities
topic <i>Arbutus unedo</i>
strawberry tree
antioxidant
phenolic compounds
arbutin
antitumoral
url https://www.mdpi.com/2304-8158/11/23/3838
work_keys_str_mv AT diegomorales useofstrawberrytreeiarbutusunedoiasasourceoffunctionalfractionswithbiologicalactivities