Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism

Restless legs syndrome (RLS) is characterized by unpleasant sensations mainly in the legs. 43% of RLS-associated conditions have also been associated with systemic iron deficiency. The objective of this study was to review in the literature the relationship between iron metabolism and RLS. With an i...

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Main Authors: Paulo Daubian-Nosé, Miriam K. Frank, Andrea Maculano Esteves
Format: Article
Language:English
Published: Thieme Revinter Publicações Ltda. 2014-12-01
Series:Sleep Science
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S198400631400056X
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author Paulo Daubian-Nosé
Miriam K. Frank
Andrea Maculano Esteves
author_facet Paulo Daubian-Nosé
Miriam K. Frank
Andrea Maculano Esteves
author_sort Paulo Daubian-Nosé
collection DOAJ
description Restless legs syndrome (RLS) is characterized by unpleasant sensations mainly in the legs. 43% of RLS-associated conditions have also been associated with systemic iron deficiency. The objective of this study was to review in the literature the relationship between iron metabolism and RLS. With an initial search using the keywords combination “Iron Metabolism OR Iron Deficiency AND Restless Legs Syndrome,” 145 articles were screened, and 20 articles were selected. Few studies were found for this review in the period of 2001–2014, however, the correlation between RLS and iron was evident.
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spelling doaj.art-9d6fe864875e446fa61d03e3b955c0272024-02-03T01:00:33ZengThieme Revinter Publicações Ltda.Sleep Science1984-00632014-12-017423423710.1016/j.slsci.2014.10.002Sleep disorders: A review of the interface between restless legs syndrome and iron metabolismPaulo Daubian-NoséMiriam K. FrankAndrea Maculano EstevesRestless legs syndrome (RLS) is characterized by unpleasant sensations mainly in the legs. 43% of RLS-associated conditions have also been associated with systemic iron deficiency. The objective of this study was to review in the literature the relationship between iron metabolism and RLS. With an initial search using the keywords combination “Iron Metabolism OR Iron Deficiency AND Restless Legs Syndrome,” 145 articles were screened, and 20 articles were selected. Few studies were found for this review in the period of 2001–2014, however, the correlation between RLS and iron was evident.http://www.sciencedirect.com/science/article/pii/S198400631400056XRestless Legs SyndromeIron Deficiency AnemiaAttention Deficit Hyperactivity DisorderPregnancySupplementationIron Genes
spellingShingle Paulo Daubian-Nosé
Miriam K. Frank
Andrea Maculano Esteves
Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism
Sleep Science
Restless Legs Syndrome
Iron Deficiency Anemia
Attention Deficit Hyperactivity Disorder
Pregnancy
Supplementation
Iron Genes
title Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism
title_full Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism
title_fullStr Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism
title_full_unstemmed Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism
title_short Sleep disorders: A review of the interface between restless legs syndrome and iron metabolism
title_sort sleep disorders a review of the interface between restless legs syndrome and iron metabolism
topic Restless Legs Syndrome
Iron Deficiency Anemia
Attention Deficit Hyperactivity Disorder
Pregnancy
Supplementation
Iron Genes
url http://www.sciencedirect.com/science/article/pii/S198400631400056X
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AT miriamkfrank sleepdisordersareviewoftheinterfacebetweenrestlesslegssyndromeandironmetabolism
AT andreamaculanoesteves sleepdisordersareviewoftheinterfacebetweenrestlesslegssyndromeandironmetabolism