MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation

MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation

Summary: MicroRNA-223 is known as a myeloid-enriched anti-inflammatory microRNA that is dysregulated in numerous inflammatory conditions. Here, we report that neutrophilic inflammation (wound response) is augmented in miR-223-deficient zebrafish, due primarily to elevated activation of the canonical...

Ful tanımlama

Detaylı Bibliyografya
Asıl Yazarlar: Wenqing Zhou, Arpita S. Pal, Alan Yi-Hui Hsu, Theodore Gurol, Xiaoguang Zhu, Sara E. Wirbisky-Hershberger, Jennifer L. Freeman, Andrea L. Kasinski, Qing Deng
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Elsevier 2018-02-01
Seri Bilgileri:Cell Reports
Konular:
microRNA
miR-223
inflammation
neutrophils
NF-κB
epithelium
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2211124718301074

Internet

http://www.sciencedirect.com/science/article/pii/S2211124718301074

Benzer Materyaller