Maternal autoimmune diseases and mental disorders in children and adolescents
Introduction The influence of maternal autoimmunity mediators on child development and brain function has been the subject of several studies. Clinically, most have focused on the association between maternal autoimmunity and the diagnosis of autism in children. On the other hand, data are rarer co...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Cambridge University Press
2023-03-01
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| Series: | European Psychiatry |
| Online Access: | https://www.cambridge.org/core/product/identifier/S0924933823006326/type/journal_article |
| _version_ | 1797616010955587584 |
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| author | Z. Elmaataoui H. Belhadga H. Kisra |
| author_facet | Z. Elmaataoui H. Belhadga H. Kisra |
| author_sort | Z. Elmaataoui |
| collection | DOAJ |
| description |
Introduction
The influence of maternal autoimmunity mediators on child development and brain function has been the subject of several studies. Clinically, most have focused on the association between maternal autoimmunity and the diagnosis of autism in children. On the other hand, data are rarer concerning the rest of the mental disorders and mainly, they are obtained from small cohorts.
Objectives
The aim of this study is to discuss the association between the presence of autoimmune pathology in the mother and the development of mental disorders in the child
Methods
we conducted our study through a descriptive study of six clinical cases.
Results
80 % the patients treated were male
57% had a characterized depressive disorder
34% had ADHD
9 % had ASD
Conclusions
Maternal autoimmune diseases were associated with increased mental disorders in children. These results suggest a possible shared genetic vulnerability between the two conditions or a potential role of maternal immune activation in the expression of neurodevelopmental disorders in children.
Disclosure of Interest
None Declared |
| first_indexed | 2024-03-11T07:35:05Z |
| format | Article |
| id | doaj.art-9d707480bb464e3c90b6a9a065d1079d |
| institution | Directory Open Access Journal |
| issn | 0924-9338 1778-3585 |
| language | English |
| last_indexed | 2024-03-11T07:35:05Z |
| publishDate | 2023-03-01 |
| publisher | Cambridge University Press |
| record_format | Article |
| series | European Psychiatry |
| spelling | doaj.art-9d707480bb464e3c90b6a9a065d1079d2023-11-17T05:10:20ZengCambridge University PressEuropean Psychiatry0924-93381778-35852023-03-0166S280S28010.1192/j.eurpsy.2023.632Maternal autoimmune diseases and mental disorders in children and adolescentsZ. Elmaataoui0H. Belhadga1H. Kisra2Hospital Ar-Razi of sale, Sale, MoroccoHospital Ar-Razi of sale, Sale, MoroccoHospital Ar-Razi of sale, Sale, Morocco Introduction The influence of maternal autoimmunity mediators on child development and brain function has been the subject of several studies. Clinically, most have focused on the association between maternal autoimmunity and the diagnosis of autism in children. On the other hand, data are rarer concerning the rest of the mental disorders and mainly, they are obtained from small cohorts. Objectives The aim of this study is to discuss the association between the presence of autoimmune pathology in the mother and the development of mental disorders in the child Methods we conducted our study through a descriptive study of six clinical cases. Results 80 % the patients treated were male 57% had a characterized depressive disorder 34% had ADHD 9 % had ASD Conclusions Maternal autoimmune diseases were associated with increased mental disorders in children. These results suggest a possible shared genetic vulnerability between the two conditions or a potential role of maternal immune activation in the expression of neurodevelopmental disorders in children. Disclosure of Interest None Declaredhttps://www.cambridge.org/core/product/identifier/S0924933823006326/type/journal_article |
| spellingShingle | Z. Elmaataoui H. Belhadga H. Kisra Maternal autoimmune diseases and mental disorders in children and adolescents European Psychiatry |
| title | Maternal autoimmune diseases and mental disorders in children and adolescents |
| title_full | Maternal autoimmune diseases and mental disorders in children and adolescents |
| title_fullStr | Maternal autoimmune diseases and mental disorders in children and adolescents |
| title_full_unstemmed | Maternal autoimmune diseases and mental disorders in children and adolescents |
| title_short | Maternal autoimmune diseases and mental disorders in children and adolescents |
| title_sort | maternal autoimmune diseases and mental disorders in children and adolescents |
| url | https://www.cambridge.org/core/product/identifier/S0924933823006326/type/journal_article |
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