Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration
ObjectiveThis study aims to assess the clinical outcomes of three transpedicular dynamic systems in treating degenerative disc disease and evaluate their impact on both clinical and radiological aspects of the operated and adjacent segments.Materials and methodsA total of 111 patients who underwent...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-12-01
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| Series: | Frontiers in Surgery |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1297790/full |
| _version_ | 1797390229352480768 |
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| author | Mehmet Kursat Karadag Mehmet Yigit Akgun Mehmet Yigit Akgun Ahmet Tulgar Basak Ozkan Ates Ozkan Ates Mehmet Ali Tepebasili Caner Gunerbuyuk Tunc Oktenoglu Tunc Oktenoglu Mehdi Sasani Mehdi Sasani Ali Fahir Ozer Ali Fahir Ozer |
| author_facet | Mehmet Kursat Karadag Mehmet Yigit Akgun Mehmet Yigit Akgun Ahmet Tulgar Basak Ozkan Ates Ozkan Ates Mehmet Ali Tepebasili Caner Gunerbuyuk Tunc Oktenoglu Tunc Oktenoglu Mehdi Sasani Mehdi Sasani Ali Fahir Ozer Ali Fahir Ozer |
| author_sort | Mehmet Kursat Karadag |
| collection | DOAJ |
| description | ObjectiveThis study aims to assess the clinical outcomes of three transpedicular dynamic systems in treating degenerative disc disease and evaluate their impact on both clinical and radiological aspects of the operated and adjacent segments.Materials and methodsA total of 111 patients who underwent posterior transpedicular short-segment dynamic system procedures for treatment of degenerative disc disease were included. The patients were categorized into three groups, namely, Group 1 (Dynesys system, n = 38), Group 2 (Safinaz screw + PEEK rod, n = 37), and Group 3 (Safinaz screw + titanium rod, n = 36). Disc regeneration in the operated segment and disc degeneration in the operated, upper, and lower adjacent segments were assessed using the Pfirrmann Classification.ResultsPostoperatively, a statistically significant difference was observed in visual analog scale and Oswestry Disability Index scores (p < 0.001). However, no statistically significant difference was seen in disc degeneration/regeneration and degeneration scores of the upper and lower adjacent segments between the preoperative and postoperative groups (p = 0.763, p = 0.518, p = 0.201). Notably, a positive effect on disc regeneration at the operated level (32.4%) was observed. No significant differences were found between the groups in terms of operation rates, screw loosening, and screw breakage after adjacent segment disease (p > 0.05).ConclusionIn patients without advanced degeneration, all three dynamic systems demonstrated the ability to prevent degeneration in the adjacent and operated segments while promoting regeneration in the operated segment. Beyond inhibiting abnormal movement in painful segments, maintaining physiological motion and providing axial distraction in the operated segment emerged as key mechanisms supporting regeneration. |
| first_indexed | 2024-03-08T23:08:46Z |
| format | Article |
| id | doaj.art-9d756366f3794a3fbabc89fc6c373fe7 |
| institution | Directory Open Access Journal |
| issn | 2296-875X |
| language | English |
| last_indexed | 2024-03-08T23:08:46Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Surgery |
| spelling | doaj.art-9d756366f3794a3fbabc89fc6c373fe72023-12-15T10:08:36ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2023-12-011010.3389/fsurg.2023.12977901297790Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regenerationMehmet Kursat Karadag0Mehmet Yigit Akgun1Mehmet Yigit Akgun2Ahmet Tulgar Basak3Ozkan Ates4Ozkan Ates5Mehmet Ali Tepebasili6Caner Gunerbuyuk7Tunc Oktenoglu8Tunc Oktenoglu9Mehdi Sasani10Mehdi Sasani11Ali Fahir Ozer12Ali Fahir Ozer13Department of Neurosurgery, Ataturk University, Erzurum, TürkiyeDepartment of Neurosurgery, Koc University Hospital, Istanbul, TürkiyeSpine Center, Koc University Hospital, Istanbul, TürkiyeDepartment of Neurosurgery, American Hospital, Istanbul, TürkiyeDepartment of Neurosurgery, Koc University Hospital, Istanbul, TürkiyeSpine Center, Koc University Hospital, Istanbul, TürkiyeDepartment of Neurosurgery, Koc University Hospital, Istanbul, TürkiyeSpine Center, Koc University Hospital, Istanbul, TürkiyeDepartment of Neurosurgery, Koc University Hospital, Istanbul, TürkiyeSpine Center, Koc University Hospital, Istanbul, TürkiyeDepartment of Neurosurgery, Koc University Hospital, Istanbul, TürkiyeSpine Center, Koc University Hospital, Istanbul, TürkiyeDepartment of Neurosurgery, Koc University Hospital, Istanbul, TürkiyeSpine Center, Koc University Hospital, Istanbul, TürkiyeObjectiveThis study aims to assess the clinical outcomes of three transpedicular dynamic systems in treating degenerative disc disease and evaluate their impact on both clinical and radiological aspects of the operated and adjacent segments.Materials and methodsA total of 111 patients who underwent posterior transpedicular short-segment dynamic system procedures for treatment of degenerative disc disease were included. The patients were categorized into three groups, namely, Group 1 (Dynesys system, n = 38), Group 2 (Safinaz screw + PEEK rod, n = 37), and Group 3 (Safinaz screw + titanium rod, n = 36). Disc regeneration in the operated segment and disc degeneration in the operated, upper, and lower adjacent segments were assessed using the Pfirrmann Classification.ResultsPostoperatively, a statistically significant difference was observed in visual analog scale and Oswestry Disability Index scores (p < 0.001). However, no statistically significant difference was seen in disc degeneration/regeneration and degeneration scores of the upper and lower adjacent segments between the preoperative and postoperative groups (p = 0.763, p = 0.518, p = 0.201). Notably, a positive effect on disc regeneration at the operated level (32.4%) was observed. No significant differences were found between the groups in terms of operation rates, screw loosening, and screw breakage after adjacent segment disease (p > 0.05).ConclusionIn patients without advanced degeneration, all three dynamic systems demonstrated the ability to prevent degeneration in the adjacent and operated segments while promoting regeneration in the operated segment. Beyond inhibiting abnormal movement in painful segments, maintaining physiological motion and providing axial distraction in the operated segment emerged as key mechanisms supporting regeneration.https://www.frontiersin.org/articles/10.3389/fsurg.2023.1297790/fulldisc regenerationdisc degenerationlumbar dynamic systemslordosis angleintervertebral disc |
| spellingShingle | Mehmet Kursat Karadag Mehmet Yigit Akgun Mehmet Yigit Akgun Ahmet Tulgar Basak Ozkan Ates Ozkan Ates Mehmet Ali Tepebasili Caner Gunerbuyuk Tunc Oktenoglu Tunc Oktenoglu Mehdi Sasani Mehdi Sasani Ali Fahir Ozer Ali Fahir Ozer Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration Frontiers in Surgery disc regeneration disc degeneration lumbar dynamic systems lordosis angle intervertebral disc |
| title | Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration |
| title_full | Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration |
| title_fullStr | Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration |
| title_full_unstemmed | Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration |
| title_short | Clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration |
| title_sort | clinical and radiological analysis of the effects of three different lumbar transpedicular dynamic stabilization system on disc degeneration and regeneration |
| topic | disc regeneration disc degeneration lumbar dynamic systems lordosis angle intervertebral disc |
| url | https://www.frontiersin.org/articles/10.3389/fsurg.2023.1297790/full |
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