Combination therapy of brain radiotherapy and EGFR-TKIs is more effective than TKIs alone for EGFR-mutant lung adenocarcinoma patients with asymptomatic brain metastasis

Combination therapy of brain radiotherapy and EGFR-TKIs is more effective than TKIs alone for EGFR-mutant lung adenocarcinoma patients with asymptomatic brain metastasis

Abstract Background The treatment strategy for brain metastasis (BM) in patients with epidermal growth factor receptor (EGFR) -mutant lung adenocarcinoma (LAC) remains controversial. In the present study, we compared the efficacy of brain radiotherapy (RT) in combination with tyrosine kinase inhibit...

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Bibliographic Details
Main Authors: Yanxin Chen, Jianping Wei, Jing Cai, Anwen Liu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:BMC Cancer
Subjects:
EGFR-TKIs
Lung adenocarcinoma
Brain metastasis
Radiotherapy
Online Access:http://link.springer.com/article/10.1186/s12885-019-6005-6

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