Looking at Alzheimer’s Disease Pathogenesis from the Nuclear Side

Looking at Alzheimer’s Disease Pathogenesis from the Nuclear Side

Alzheimer’s disease (AD) is a neurodegenerative disorder representing the most common form of dementia. It is biologically characterized by the deposition of extracellular amyloid-β (Aβ) senile plaques and intracellular neurofibrillary tangles, constituted by hyperphosphorylated tau protein. The key...

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Bibliographic Details
Main Authors: Laura D’Andrea, Ramona Stringhi, Monica Di Luca, Elena Marcello
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biomolecules
Subjects:
Alzheimer’s disease
transcription
amyloid-β
AICD
tau
<i>APOE ε4</i>
Online Access:https://www.mdpi.com/2218-273X/11/9/1261

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