Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma
Abstract Background To investigate posture-induced changes in intraocular pressure (IOP) after ab externo XEN45 Gel-Stent implantation in patients with medically uncontrolled primary open-angle glaucoma (POAG). Methods This prospective study included thirty-two eyes with POAG that underwent XEN45 Ge...
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| Format: | Article |
| Language: | English |
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BMC
2022-12-01
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| Series: | BMC Ophthalmology |
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| Online Access: | https://doi.org/10.1186/s12886-022-02760-w |
| _version_ | 1828083417941540864 |
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| author | Hyung Nam Jin Jeong Woo Nam Haowei Zhang Mi Sun Sung Sang Woo Park |
| author_facet | Hyung Nam Jin Jeong Woo Nam Haowei Zhang Mi Sun Sung Sang Woo Park |
| author_sort | Hyung Nam Jin |
| collection | DOAJ |
| description | Abstract Background To investigate posture-induced changes in intraocular pressure (IOP) after ab externo XEN45 Gel-Stent implantation in patients with medically uncontrolled primary open-angle glaucoma (POAG). Methods This prospective study included thirty-two eyes with POAG that underwent XEN45 Gel-Stent implantation as a standalone procedure using an ab externo approach at Chonnam National University Hospital. IOP was measured sequentially in the sitting position, supine position, and lateral decubitus position (LDP) before and at 1, 2, 3, and 6 months after surgery using an iCare IC200 rebound tonometer. In the LDP, the eye with XEN45 Gel-Stent implantation was in the dependent position. Results IOP at each position was significantly reduced after XEN45 Gel-Stent implantation. Posture-induced changes in IOP were maintained during the follow-up. The range of postural IOP changes was reduced at 1 month; however, no significant change was observed after that point compared with baseline levels. Conclusions A XEN45 Gel-Stent inserted using the ab externo approach can reduce IOP in various body positions, but seems to have limited effects on posture-induced changes in IOP in patients with POAG. |
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| format | Article |
| id | doaj.art-9d7b39f6bcd04edc9b6395b630ebb85e |
| institution | Directory Open Access Journal |
| issn | 1471-2415 |
| language | English |
| last_indexed | 2024-04-11T04:08:46Z |
| publishDate | 2022-12-01 |
| publisher | BMC |
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| series | BMC Ophthalmology |
| spelling | doaj.art-9d7b39f6bcd04edc9b6395b630ebb85e2023-01-01T12:15:29ZengBMCBMC Ophthalmology1471-24152022-12-0122111010.1186/s12886-022-02760-wPosture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucomaHyung Nam Jin0Jeong Woo Nam1Haowei Zhang2Mi Sun Sung3Sang Woo Park4Department of Ophthalmology, Chonnam National University Medical School and HospitalDepartment of Ophthalmology, Chonnam National University Medical School and HospitalDepartment of Ophthalmology, Chonnam National University Medical School and HospitalDepartment of Ophthalmology, Chonnam National University Medical School and HospitalDepartment of Ophthalmology, Chonnam National University Medical School and HospitalAbstract Background To investigate posture-induced changes in intraocular pressure (IOP) after ab externo XEN45 Gel-Stent implantation in patients with medically uncontrolled primary open-angle glaucoma (POAG). Methods This prospective study included thirty-two eyes with POAG that underwent XEN45 Gel-Stent implantation as a standalone procedure using an ab externo approach at Chonnam National University Hospital. IOP was measured sequentially in the sitting position, supine position, and lateral decubitus position (LDP) before and at 1, 2, 3, and 6 months after surgery using an iCare IC200 rebound tonometer. In the LDP, the eye with XEN45 Gel-Stent implantation was in the dependent position. Results IOP at each position was significantly reduced after XEN45 Gel-Stent implantation. Posture-induced changes in IOP were maintained during the follow-up. The range of postural IOP changes was reduced at 1 month; however, no significant change was observed after that point compared with baseline levels. Conclusions A XEN45 Gel-Stent inserted using the ab externo approach can reduce IOP in various body positions, but seems to have limited effects on posture-induced changes in IOP in patients with POAG.https://doi.org/10.1186/s12886-022-02760-wXEN45 gel-stentAb externoPosture-induced changes in IOPRebound tonometry |
| spellingShingle | Hyung Nam Jin Jeong Woo Nam Haowei Zhang Mi Sun Sung Sang Woo Park Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma BMC Ophthalmology XEN45 gel-stent Ab externo Posture-induced changes in IOP Rebound tonometry |
| title | Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma |
| title_full | Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma |
| title_fullStr | Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma |
| title_full_unstemmed | Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma |
| title_short | Posture-induced changes in intraocular pressure after ab externo XEN45 gel-stent implantation in patients with primary open-angle glaucoma |
| title_sort | posture induced changes in intraocular pressure after ab externo xen45 gel stent implantation in patients with primary open angle glaucoma |
| topic | XEN45 gel-stent Ab externo Posture-induced changes in IOP Rebound tonometry |
| url | https://doi.org/10.1186/s12886-022-02760-w |
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