Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes

Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic t...

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Main Authors: Aisha Hamidu, William G. Pitt, Ghaleb A. Husseini
Format: Article
Language:English
Published: MDPI AG 2023-09-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/13/18/2566
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author Aisha Hamidu
William G. Pitt
Ghaleb A. Husseini
author_facet Aisha Hamidu
William G. Pitt
Ghaleb A. Husseini
author_sort Aisha Hamidu
collection DOAJ
description Cancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic techniques. Quantum dots (QDs) are functional nanoparticles reported to be useful for diagnosis. QDs are semiconducting tiny nanocrystals, 2–10 nm in diameter, with exceptional and useful optoelectronic properties that can be tailored to sensitively report on their environment. This review highlights these exceptional semiconducting QDs and their properties and synthesis methods when used in cancer diagnostics. The conjugation of reporting or binding molecules to the QD surface is discussed. This review summarizes the most recent advances in using QDs for in vitro imaging, in vivo imaging, and targeted drug delivery platforms in cancer applications.
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spelling doaj.art-9d7dd33f3881408289c6946888fcd6f42023-11-19T12:14:46ZengMDPI AGNanomaterials2079-49912023-09-011318256610.3390/nano13182566Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery PurposesAisha Hamidu0William G. Pitt1Ghaleb A. Husseini2Biomedical Engineering Program, College of Engineering, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesDepartment of Chemical Engineering, Brigham Young University, Provo, UT 84602, USAMaterials Science and Engineering Program, College of Arts and Sciences, American University of Sharjah, Sharjah P.O. Box 26666, United Arab EmiratesCancer is one of the leading causes of death worldwide. Because each person’s cancer may be unique, diagnosing and treating cancer is challenging. Advances in nanomedicine have made it possible to detect tumors and quickly investigate tumor cells at a cellular level in contrast to prior diagnostic techniques. Quantum dots (QDs) are functional nanoparticles reported to be useful for diagnosis. QDs are semiconducting tiny nanocrystals, 2–10 nm in diameter, with exceptional and useful optoelectronic properties that can be tailored to sensitively report on their environment. This review highlights these exceptional semiconducting QDs and their properties and synthesis methods when used in cancer diagnostics. The conjugation of reporting or binding molecules to the QD surface is discussed. This review summarizes the most recent advances in using QDs for in vitro imaging, in vivo imaging, and targeted drug delivery platforms in cancer applications.https://www.mdpi.com/2079-4991/13/18/2566quantum dotsfunctionalizationin vitro imagingin vivo imagingdrug delivery
spellingShingle Aisha Hamidu
William G. Pitt
Ghaleb A. Husseini
Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
Nanomaterials
quantum dots
functionalization
in vitro imaging
in vivo imaging
drug delivery
title Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_full Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_fullStr Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_full_unstemmed Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_short Recent Breakthroughs in Using Quantum Dots for Cancer Imaging and Drug Delivery Purposes
title_sort recent breakthroughs in using quantum dots for cancer imaging and drug delivery purposes
topic quantum dots
functionalization
in vitro imaging
in vivo imaging
drug delivery
url https://www.mdpi.com/2079-4991/13/18/2566
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