Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC

Chronic hepatitis B virus (HBV) infection is a worldwide public health threat that results in huge morbidity and mortality. Late diagnosis and delayed treatment of HBV infections can cause irreversible liver damages and occurrence of cirrhosis and hepatocellular carcinoma (HCC). Detection of the pre...

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Main Authors: Wanting Shi, Kang Li, Yonghong Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2023.1185142/full
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author Wanting Shi
Kang Li
Yonghong Zhang
author_facet Wanting Shi
Kang Li
Yonghong Zhang
author_sort Wanting Shi
collection DOAJ
description Chronic hepatitis B virus (HBV) infection is a worldwide public health threat that results in huge morbidity and mortality. Late diagnosis and delayed treatment of HBV infections can cause irreversible liver damages and occurrence of cirrhosis and hepatocellular carcinoma (HCC). Detection of the presence and activity of HBV are the cornerstones of diagnosis and management in HBV related disease. Moreover, comprehensive knowledge of the mechanisms regulating HBV immunobiology is pivotal for managing diseases related with HBV. Here we tried to categorize and illustrate the classical and novel approaches used for diagnosis of HBV. Also, we reviewed our current knowledge on the immunobiology of HBV related HCC.
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spelling doaj.art-9d7ff27a7c3443de9d90f29a3884f9a12023-11-28T22:33:39ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-11-011310.3389/fonc.2023.11851421185142Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCCWanting Shi0Kang Li1Yonghong Zhang2Interventional Therapy Center of Liver Disease, Beijing You'An Hospital, Capital Medical University, Beijing, ChinaBiomedical Information Center, Beijing You'An Hospital, Capital Medical University, Beijing, ChinaInterventional Therapy Center of Liver Disease, Beijing You'An Hospital, Capital Medical University, Beijing, ChinaChronic hepatitis B virus (HBV) infection is a worldwide public health threat that results in huge morbidity and mortality. Late diagnosis and delayed treatment of HBV infections can cause irreversible liver damages and occurrence of cirrhosis and hepatocellular carcinoma (HCC). Detection of the presence and activity of HBV are the cornerstones of diagnosis and management in HBV related disease. Moreover, comprehensive knowledge of the mechanisms regulating HBV immunobiology is pivotal for managing diseases related with HBV. Here we tried to categorize and illustrate the classical and novel approaches used for diagnosis of HBV. Also, we reviewed our current knowledge on the immunobiology of HBV related HCC.https://www.frontiersin.org/articles/10.3389/fonc.2023.1185142/fullhepatitis B virus (HBV) infectionhepatocellular carcinomaimmune responsesdiagnosismanagement
spellingShingle Wanting Shi
Kang Li
Yonghong Zhang
Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC
Frontiers in Oncology
hepatitis B virus (HBV) infection
hepatocellular carcinoma
immune responses
diagnosis
management
title Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC
title_full Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC
title_fullStr Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC
title_full_unstemmed Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC
title_short Current tests for diagnosis of hepatitis B virus infection and immune responses of HBV-related HCC
title_sort current tests for diagnosis of hepatitis b virus infection and immune responses of hbv related hcc
topic hepatitis B virus (HBV) infection
hepatocellular carcinoma
immune responses
diagnosis
management
url https://www.frontiersin.org/articles/10.3389/fonc.2023.1185142/full
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