A negative feedback loop in the GPCR pathway underlies efficient coding of external stimuli

A negative feedback loop in the GPCR pathway underlies efficient coding of external stimuli

Abstract Efficient navigation based on chemical cues is an essential feature shared by all animals. These cues may be encountered in complex spatiotemporal patterns and with orders of magnitude varying intensities. Nevertheless, sensory neurons accurately extract the relevant information from such p...

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Bibliographic Details
Main Authors: Rotem Ruach, Shai Yellinek, Eyal Itskovits, Noa Deshe, Yifat Eliezer, Eduard Bokman, Alon Zaslaver
Format: Article
Language:English
Published: Springer Nature 2022-09-01
Series:Molecular Systems Biology
Subjects:
calcineurin/TAX‐6
calcium imaging
GPCR signaling
negative feedback
pulsatile response
Online Access:https://doi.org/10.15252/msb.202110514

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