Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets
Abstract Infectious pathogens can be transmitted through textiles. Therefore, additional efforts are needed to develop functional fabrics containing antimicrobial substances to prevent the growth of antibiotic-resistant bacteria and their biofilms. Here, we developed a cotton fabric coated with redu...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2023-07-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-38723-4 |
| _version_ | 1797769588548567040 |
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| author | Jiwon Kim Seung Hyun Kang Yonghyun Choi Wonjae Lee Nayeong Kim Masayoshi Tanaka Shink Hyuk Kang Jonghoon Choi |
| author_facet | Jiwon Kim Seung Hyun Kang Yonghyun Choi Wonjae Lee Nayeong Kim Masayoshi Tanaka Shink Hyuk Kang Jonghoon Choi |
| author_sort | Jiwon Kim |
| collection | DOAJ |
| description | Abstract Infectious pathogens can be transmitted through textiles. Therefore, additional efforts are needed to develop functional fabrics containing antimicrobial substances to prevent the growth of antibiotic-resistant bacteria and their biofilms. Here, we developed a cotton fabric coated with reduced graphene oxide (rGO) and copper nanoparticles (Cu NPs), which possessed hydrophobic, antimicrobial, and anti-biofilm properties. Once the graphene oxide was dip-coated on a cellulose cotton fabric, Cu NPs were synthesized using a chemical reduction method to fabricate an rGO/Cu fabric, which was analyzed through FE-SEM, EDS, and ICP-MS. The results of our colony-forming unit assays indicated that the rGO/Cu fabric possessed high antibacterial and anti-biofilm properties against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, Corynebacterium xerosis, and Micrococcus luteus. Particularly, the fabric could inhibit the growth of E. coli, C. xerosis, and M. luteus with a 99% efficiency. Furthermore, our findings confirmed that the same concentrations of rGO/Cu had no cytotoxic effects against CCD-986Sk and Human Dermal Fibroblast (HDF), human skin cells, and NIH/3T3, a mouse skin cell. The developed rGO/Cu fabric thus exhibited promising applicability as a cotton material that can maintain hygienic conditions by preventing the propagation of various bacteria and sufficiently suppressing biofilm formation while also being harmless to the human body. |
| first_indexed | 2024-03-12T21:10:12Z |
| format | Article |
| id | doaj.art-9d8728382f56449c9a35d50d3c1bd077 |
| institution | Directory Open Access Journal |
| issn | 2045-2322 |
| language | English |
| last_indexed | 2024-03-12T21:10:12Z |
| publishDate | 2023-07-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj.art-9d8728382f56449c9a35d50d3c1bd0772023-07-30T11:12:45ZengNature PortfolioScientific Reports2045-23222023-07-0113111110.1038/s41598-023-38723-4Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheetsJiwon Kim0Seung Hyun Kang1Yonghyun Choi2Wonjae Lee3Nayeong Kim4Masayoshi Tanaka5Shink Hyuk Kang6Jonghoon Choi7School of Integrative Engineering, Chung-Ang UniversityDepartment of Plastic and Reconstructive Surgery, Chung-Ang University Hospital, Chung-Ang University College of MedicineSchool of Integrative Engineering, Chung-Ang UniversitySchool of Integrative Engineering, Chung-Ang UniversitySchool of Integrative Engineering, Chung-Ang UniversityDepartment of Chemical Science and Engineering, Tokyo Institute of TechnologyDepartment of Plastic and Reconstructive Surgery, Chung-Ang University Hospital, Chung-Ang University College of MedicineSchool of Integrative Engineering, Chung-Ang UniversityAbstract Infectious pathogens can be transmitted through textiles. Therefore, additional efforts are needed to develop functional fabrics containing antimicrobial substances to prevent the growth of antibiotic-resistant bacteria and their biofilms. Here, we developed a cotton fabric coated with reduced graphene oxide (rGO) and copper nanoparticles (Cu NPs), which possessed hydrophobic, antimicrobial, and anti-biofilm properties. Once the graphene oxide was dip-coated on a cellulose cotton fabric, Cu NPs were synthesized using a chemical reduction method to fabricate an rGO/Cu fabric, which was analyzed through FE-SEM, EDS, and ICP-MS. The results of our colony-forming unit assays indicated that the rGO/Cu fabric possessed high antibacterial and anti-biofilm properties against Escherichia coli, Pseudomonas aeruginosa, Staphylococcus epidermidis, Corynebacterium xerosis, and Micrococcus luteus. Particularly, the fabric could inhibit the growth of E. coli, C. xerosis, and M. luteus with a 99% efficiency. Furthermore, our findings confirmed that the same concentrations of rGO/Cu had no cytotoxic effects against CCD-986Sk and Human Dermal Fibroblast (HDF), human skin cells, and NIH/3T3, a mouse skin cell. The developed rGO/Cu fabric thus exhibited promising applicability as a cotton material that can maintain hygienic conditions by preventing the propagation of various bacteria and sufficiently suppressing biofilm formation while also being harmless to the human body.https://doi.org/10.1038/s41598-023-38723-4 |
| spellingShingle | Jiwon Kim Seung Hyun Kang Yonghyun Choi Wonjae Lee Nayeong Kim Masayoshi Tanaka Shink Hyuk Kang Jonghoon Choi Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets Scientific Reports |
| title | Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets |
| title_full | Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets |
| title_fullStr | Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets |
| title_full_unstemmed | Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets |
| title_short | Antibacterial and biofilm-inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets |
| title_sort | antibacterial and biofilm inhibiting cotton fabrics decorated with copper nanoparticles grown on graphene nanosheets |
| url | https://doi.org/10.1038/s41598-023-38723-4 |
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