Long-Term Hypercaloric Diet Consumption Exacerbates Age-Induced Dysmetabolism and Carotid Body Dysfunction: Beneficial Effects of CSN Denervation

Long-Term Hypercaloric Diet Consumption Exacerbates Age-Induced Dysmetabolism and Carotid Body Dysfunction: Beneficial Effects of CSN Denervation

Carotid bodies (CBs) are metabolic sensors whose dysfunction is involved in the genesis of dysmetabolic states. Ageing induces significant alterations in CB function also prompting to metabolic deregulation. On the other hand, metabolic disease can accelerate ageing processes. Taking these into acco...

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Bibliographic Details
Main Authors: Bernardete F. Melo, Joana F. Sacramento, Adriana M. Capucho, Dinis Sampaio-Pires, Cláudia S. Prego, Silvia V. Conde
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-05-01
Series:Frontiers in Physiology
Subjects:
carotid body
metabolic disease
ageing
hypercaloric diets
carotid sinus nerve
insulin receptor
Online Access:https://www.frontiersin.org/articles/10.3389/fphys.2022.889660/full

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