Investigating the impact of human blood metabolites on the Sepsis development and progression: a study utilizing two-sample Mendelian randomization

Investigating the impact of human blood metabolites on the Sepsis development and progression: a study utilizing two-sample Mendelian randomization

BackgroundExisting data suggests a potential link between human blood metabolites and sepsis, yet the precise cause-and-effect relationship remains elusive. By using a two-sample Mendelian randomization (MR) analysis, this study aims to establish a causal link between human blood metabolites and sep...

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Bibliographic Details
Main Authors: Zhongqi Zhang, Yu Yin, Tingzhen Chen, Jinjin You, Wenhui Zhang, Yifan Zhao, Yankang Ren, Han Wang, Xiangding Chen, Xiangrong Zuo
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-12-01
Series:Frontiers in Medicine
Subjects:
sepsis
metabolites
two-sample mendelian randomization
causal inference
mortality
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2023.1310391/full

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