Galectin-9 contributes to the pathogenesis of atopic dermatitis via T cell immunoglobulin mucin-3

Galectin-9 contributes to the pathogenesis of atopic dermatitis via T cell immunoglobulin mucin-3

BackgroundAtopic dermatitis (AD), a common type 2 inflammatory disease, is driven by T helper (TH) 2/TH22polarization and cytokines.Galectin-9 (Gal-9), via its receptor T cell immunoglobulin- and mucin-domain-containing molecule-3 (TIM-3), can promote TH2/TH22 immunity. The relevance of this in AD i...

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Bibliographic Details
Main Authors: Wenxing Su, Ji Zhang, Shun Yang, Minhui Tang, Yu Shen, Cuiping Liu, Jiang Ji, Marcus Maurer, Qingqing Jiao
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Immunology
Subjects:
T cell immunoglobulin- and mucin-domain-containing molecules-3 (TIM-3)
Galectin-9 (Gal-9)
TH1 cells
TH2 cells
TH17 cells
TH22 cells
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.952338/full

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