Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey
OBJECTIVES: Restless legs syndrome (RLS) is a frequent comorbid condition associated with distinct unrelated diseases. While the incidence of RLS has not been definitively confirmed, RLS-like symptoms have been reported in a section of Asian population who also had hyperthyroidism. The prevalence of...
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| Format: | Article |
| Language: | English |
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Elsevier España
2020-11-01
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| Series: | Clinics |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100302&tlng=en |
| _version_ | 1811229543830126592 |
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| author | Marcia Pradella-Hallinan José Carlos Pereira Jr. João Roberto Maciel Martins |
| author_facet | Marcia Pradella-Hallinan José Carlos Pereira Jr. João Roberto Maciel Martins |
| author_sort | Marcia Pradella-Hallinan |
| collection | DOAJ |
| description | OBJECTIVES: Restless legs syndrome (RLS) is a frequent comorbid condition associated with distinct unrelated diseases. While the incidence of RLS has not been definitively confirmed, RLS-like symptoms have been reported in a section of Asian population who also had hyperthyroidism. The prevalence of RLS is generally low in Asian populations. Under these circumstances, we hypothesized that in a population where RLS is common, such as in Brazil, RLS could manifest as a comorbid ailment alongside Graves’ disease, a common hyperthyroid condition. METHODS: In a cross-sectional survey, 108 patients who presented with Graves' disease were analyzed for restless legs or associated symptoms. RESULTS: Twelve patients (11.1%) displayed symptoms of RLS prior to the incidence of Graves’ disease. These patients experienced worsening of the symptoms during their hyperthyroid state. Six patients (5.6%) developed RLS, consequent upon the incidence of Graves’ disease as per the consensus of the panel of the experts. Fifteen patients (13.9%) also presented with RLS-like symptoms without any discernible circadian feature of the syndrome. CONCLUSION: Our findings confirm that Graves’ disease might trigger restless legs-like symptoms, while the condition of hyperthyroidism could also be complicated by definite RLS. |
| first_indexed | 2024-04-12T10:17:04Z |
| format | Article |
| id | doaj.art-9d939c8d9cf642baaf259751f572c35b |
| institution | Directory Open Access Journal |
| issn | 1980-5322 |
| language | English |
| last_indexed | 2024-04-12T10:17:04Z |
| publishDate | 2020-11-01 |
| publisher | Elsevier España |
| record_format | Article |
| series | Clinics |
| spelling | doaj.art-9d939c8d9cf642baaf259751f572c35b2022-12-22T03:37:11ZengElsevier EspañaClinics1980-53222020-11-017510.6061/clinics/2020/e2140Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional surveyMarcia Pradella-Hallinanhttps://orcid.org/0000-0003-3591-9482José Carlos Pereira Jr.https://orcid.org/0000-0002-7927-1457João Roberto Maciel Martinshttps://orcid.org/0000-0002-0204-3552OBJECTIVES: Restless legs syndrome (RLS) is a frequent comorbid condition associated with distinct unrelated diseases. While the incidence of RLS has not been definitively confirmed, RLS-like symptoms have been reported in a section of Asian population who also had hyperthyroidism. The prevalence of RLS is generally low in Asian populations. Under these circumstances, we hypothesized that in a population where RLS is common, such as in Brazil, RLS could manifest as a comorbid ailment alongside Graves’ disease, a common hyperthyroid condition. METHODS: In a cross-sectional survey, 108 patients who presented with Graves' disease were analyzed for restless legs or associated symptoms. RESULTS: Twelve patients (11.1%) displayed symptoms of RLS prior to the incidence of Graves’ disease. These patients experienced worsening of the symptoms during their hyperthyroid state. Six patients (5.6%) developed RLS, consequent upon the incidence of Graves’ disease as per the consensus of the panel of the experts. Fifteen patients (13.9%) also presented with RLS-like symptoms without any discernible circadian feature of the syndrome. CONCLUSION: Our findings confirm that Graves’ disease might trigger restless legs-like symptoms, while the condition of hyperthyroidism could also be complicated by definite RLS.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100302&tlng=enRestless Legs SyndromeWillis-Ekbom DiseaseGraves’ Disease |
| spellingShingle | Marcia Pradella-Hallinan José Carlos Pereira Jr. João Roberto Maciel Martins Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey Clinics Restless Legs Syndrome Willis-Ekbom Disease Graves’ Disease |
| title | Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey |
| title_full | Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey |
| title_fullStr | Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey |
| title_full_unstemmed | Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey |
| title_short | Restless Legs Syndrome, and symptoms of Restless Syndrome in patients with Graves’ disease: a cross-sectional survey |
| title_sort | restless legs syndrome and symptoms of restless syndrome in patients with graves disease a cross sectional survey |
| topic | Restless Legs Syndrome Willis-Ekbom Disease Graves’ Disease |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1807-59322020000100302&tlng=en |
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