FeTPPS, a Peroxynitrite Decomposition Catalyst, Ameliorates Nitrosative Stress in Human Spermatozoa

FeTPPS, a Peroxynitrite Decomposition Catalyst, Ameliorates Nitrosative Stress in Human Spermatozoa

Excessive levels of reactive nitrogen species (RNS), such as peroxynitrite, promote nitrosative stress, which is an important cause of impaired sperm function. The metalloporphyrin FeTPPS is highly effective in catalyzing the decomposition of peroxynitrite, reducing its toxic effects in vivo and in...

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Bibliographic Details
Main Authors: Pamela Uribe, Javiera Barra, Kevin Painen, Fabiola Zambrano, Mabel Schulz, Claudia Moya, Vladimir Isachenko, Evgenia Isachenko, Peter Mallmann, Raúl Sánchez
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:Antioxidants
Subjects:
nitrosative stress
peroxynitrite
human sperm
antioxidant
Online Access:https://www.mdpi.com/2076-3921/12/6/1272

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