Neuroendocrine Tumours: a Literature Review

Neuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from th...

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Main Authors: K. V. Menshikov, A. V. Sultanbaev, Sh. I. Musin, I. A. Menshikova, A. F. Nasretdinov, N. I. Sultanbaeva, I. R. Shaykhutdinov
Format: Article
Language:English
Published: Bashkir State Medical University 2021-05-01
Series:Креативная хирургия и онкология
Subjects:
Online Access:https://www.surgonco.ru/jour/article/view/588
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author K. V. Menshikov
A. V. Sultanbaev
Sh. I. Musin
I. A. Menshikova
A. F. Nasretdinov
N. I. Sultanbaeva
I. R. Shaykhutdinov
author_facet K. V. Menshikov
A. V. Sultanbaev
Sh. I. Musin
I. A. Menshikova
A. F. Nasretdinov
N. I. Sultanbaeva
I. R. Shaykhutdinov
author_sort K. V. Menshikov
collection DOAJ
description Neuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from the central nervous system, respiratory and gastrointestinal tracts, larynx, thyroid, skin, breast and urogenital system. The evidence on NET prevalence is diverse, with selected sources estimating a 0.5% rate among total malignancies diagnosed. Carcinoid syndrome is a known important associate of NETs. Its presence resulting from the amine and peptide hypersecretion often facilitates the NET diagnosis, and curative surgery becomes a treatment of choice, if technically feasible. Adjuvant therapy is ambiguous. When surgery is impractical due to a usually advanced NET at diagnosis, drug therapy is adopted to relief symptoms and control the disease.
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spelling doaj.art-9d96be37f5e4432488cd8ab75a7b2ba02023-03-13T10:01:10ZengBashkir State Medical UniversityКреативная хирургия и онкология2307-05012076-30932021-05-0111217418210.24060/2076-3093-2021-11-2-174-182433Neuroendocrine Tumours: a Literature ReviewK. V. Menshikov0A. V. Sultanbaev1Sh. I. Musin2I. A. Menshikova3A. F. Nasretdinov4N. I. Sultanbaeva5I. R. Shaykhutdinov6Республиканский клинический онкологический диспансер; Башкирский государственный медицинский университетРеспубликанский клинический онкологический диспансерРеспубликанский клинический онкологический диспансерБашкирский государственный медицинский университетРеспубликанский клинический онкологический диспансерРеспубликанский клинический онкологический диспансерБашкирский государственный медицинский университетNeuroendocrine tumours (NETs) are a heterogeneous group of malignant neoplasms with diverse morphology and nomenclature. Well-differentiated NETs were historically termed carcinoid tumours, which entailed abundant confusion and misclassification. Cross body-localised NETs have been described from the central nervous system, respiratory and gastrointestinal tracts, larynx, thyroid, skin, breast and urogenital system. The evidence on NET prevalence is diverse, with selected sources estimating a 0.5% rate among total malignancies diagnosed. Carcinoid syndrome is a known important associate of NETs. Its presence resulting from the amine and peptide hypersecretion often facilitates the NET diagnosis, and curative surgery becomes a treatment of choice, if technically feasible. Adjuvant therapy is ambiguous. When surgery is impractical due to a usually advanced NET at diagnosis, drug therapy is adopted to relief symptoms and control the disease.https://www.surgonco.ru/jour/article/view/588нейроэндокринная опухолькарциноидкарциноидный синдроманалоги соматостатинаклассификация опухолей
spellingShingle K. V. Menshikov
A. V. Sultanbaev
Sh. I. Musin
I. A. Menshikova
A. F. Nasretdinov
N. I. Sultanbaeva
I. R. Shaykhutdinov
Neuroendocrine Tumours: a Literature Review
Креативная хирургия и онкология
нейроэндокринная опухоль
карциноид
карциноидный синдром
аналоги соматостатина
классификация опухолей
title Neuroendocrine Tumours: a Literature Review
title_full Neuroendocrine Tumours: a Literature Review
title_fullStr Neuroendocrine Tumours: a Literature Review
title_full_unstemmed Neuroendocrine Tumours: a Literature Review
title_short Neuroendocrine Tumours: a Literature Review
title_sort neuroendocrine tumours a literature review
topic нейроэндокринная опухоль
карциноид
карциноидный синдром
аналоги соматостатина
классификация опухолей
url https://www.surgonco.ru/jour/article/view/588
work_keys_str_mv AT kvmenshikov neuroendocrinetumoursaliteraturereview
AT avsultanbaev neuroendocrinetumoursaliteraturereview
AT shimusin neuroendocrinetumoursaliteraturereview
AT iamenshikova neuroendocrinetumoursaliteraturereview
AT afnasretdinov neuroendocrinetumoursaliteraturereview
AT nisultanbaeva neuroendocrinetumoursaliteraturereview
AT irshaykhutdinov neuroendocrinetumoursaliteraturereview