CSF levels of Chitinase3like1 correlate with early response to cladribine in multiple sclerosis

CSF levels of Chitinase3like1 correlate with early response to cladribine in multiple sclerosis

BackgroundCladribine has been introduced as a high-efficacy drug for treating relapsing-remitting multiple sclerosis (RRMS). Initial cohort studies showed early disease activity in the first year after drug initiation. Biomarkers that can predict early disease activity are needed.AimTo estimate cere...

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Main Authors: Damiano Marastoni, Matteo Foschi, Chiara Eccher, Francesco Crescenzo, Valentina Mazziotti, Agnese Tamanti, Albulena Bajrami, Valentina Camera, Stefano Ziccardi, Maddalena Guandalini, Francesca Bosello, Daniela Anni, Federica Virla, Ermanna Turano, Michele Romoli, Raffaella Mariotti, Francesca Benedetta Pizzini, Bruno Bonetti, Massimiliano Calabrese
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-02-01
Series:Frontiers in Immunology
Subjects:
relapsing multiple sclerosis
cytokines
chemokines
cladribine
disease activity
biomarkers
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1343892/full

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