A Rare Cause of Hypothyroidism: TSH’oma
TSH (tyrotiropin) secreting pituitary adenomas account for <1% of all hypophyseal adenomas with a prevelance of 1/1.000.000 and is a very rare reason of hyperthyroidism (TSH’oma). In these casess free t4 and free t3 levels are elevated whereas TSH levels are normal or elevated. A 26 year...
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| Format: | Article |
| Language: | English |
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Cukurova University
2013-06-01
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| Series: | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| Subjects: | |
| Online Access: | http://www.scopemed.org/fulltextpdf.php?mno=32493 |
| _version_ | 1828026552062836736 |
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| author | Okan Bakiner Emre Bozkirli A. Kursad Ozsahin Aydan Aksoyek |
| author_facet | Okan Bakiner Emre Bozkirli A. Kursad Ozsahin Aydan Aksoyek |
| author_sort | Okan Bakiner |
| collection | DOAJ |
| description | TSH (tyrotiropin) secreting pituitary adenomas account for <1% of all hypophyseal adenomas with a prevelance of 1/1.000.000 and is a very rare reason of hyperthyroidism (TSH’oma). In these casess free t4 and free t3 levels are elevated whereas TSH levels are normal or elevated. A 26 year old women referred to our outpatient clinic with complaints of palpitation, tremors, weight loss and dispnea for three months. Laboratory analysis showed that plasm free T3 levels (8,2 mIU/ml-normal 3,2-5,4 ) and TSH levels were high(5,7 mIU/ml, normal 0,3-4,9 mIU/ml), and free T4 level was on the upper limit (14,7 mIU/ml- normal 9-15 mIU/ml). Considering TSH depended hyperthyrodism the patient went under a magnetic resonance imaging scan (MRI) which confirmed an 11 mm lesion on hypophysis which was compatible with adenoma.The patient was diagnosed with TSH’oma and went under transnasal, transsphenoidal hypophysis surgery. Although TSH secreting pituitary adenomas are rare causes of hyperthyrodism, advanced laboratory methods allow them to be diagnosed early and avoid unnecessary tests and time loss. [Cukurova Med J 2013; 38(3.000): 499-502] |
| first_indexed | 2024-04-10T13:20:31Z |
| format | Article |
| id | doaj.art-9d97cf6ca68a4bd3ac6faa2ee51d1e8a |
| institution | Directory Open Access Journal |
| issn | 0250-5150 |
| language | English |
| last_indexed | 2024-04-10T13:20:31Z |
| publishDate | 2013-06-01 |
| publisher | Cukurova University |
| record_format | Article |
| series | Çukurova Üniversitesi Tıp Fakültesi Dergisi |
| spelling | doaj.art-9d97cf6ca68a4bd3ac6faa2ee51d1e8a2023-02-15T16:12:04ZengCukurova UniversityÇukurova Üniversitesi Tıp Fakültesi Dergisi0250-51502013-06-01383499502A Rare Cause of Hypothyroidism: TSH’omaOkan BakinerEmre BozkirliA. Kursad OzsahinAydan AksoyekTSH (tyrotiropin) secreting pituitary adenomas account for <1% of all hypophyseal adenomas with a prevelance of 1/1.000.000 and is a very rare reason of hyperthyroidism (TSH’oma). In these casess free t4 and free t3 levels are elevated whereas TSH levels are normal or elevated. A 26 year old women referred to our outpatient clinic with complaints of palpitation, tremors, weight loss and dispnea for three months. Laboratory analysis showed that plasm free T3 levels (8,2 mIU/ml-normal 3,2-5,4 ) and TSH levels were high(5,7 mIU/ml, normal 0,3-4,9 mIU/ml), and free T4 level was on the upper limit (14,7 mIU/ml- normal 9-15 mIU/ml). Considering TSH depended hyperthyrodism the patient went under a magnetic resonance imaging scan (MRI) which confirmed an 11 mm lesion on hypophysis which was compatible with adenoma.The patient was diagnosed with TSH’oma and went under transnasal, transsphenoidal hypophysis surgery. Although TSH secreting pituitary adenomas are rare causes of hyperthyrodism, advanced laboratory methods allow them to be diagnosed early and avoid unnecessary tests and time loss. [Cukurova Med J 2013; 38(3.000): 499-502]http://www.scopemed.org/fulltextpdf.php?mno=32493TSH’omaPitiutary AdenomaHyperthyroidism, |
| spellingShingle | Okan Bakiner Emre Bozkirli A. Kursad Ozsahin Aydan Aksoyek A Rare Cause of Hypothyroidism: TSH’oma Çukurova Üniversitesi Tıp Fakültesi Dergisi TSH’oma Pitiutary Adenoma Hyperthyroidism, |
| title | A Rare Cause of Hypothyroidism: TSH’oma |
| title_full | A Rare Cause of Hypothyroidism: TSH’oma |
| title_fullStr | A Rare Cause of Hypothyroidism: TSH’oma |
| title_full_unstemmed | A Rare Cause of Hypothyroidism: TSH’oma |
| title_short | A Rare Cause of Hypothyroidism: TSH’oma |
| title_sort | rare cause of hypothyroidism tsh 146 oma |
| topic | TSH’oma Pitiutary Adenoma Hyperthyroidism, |
| url | http://www.scopemed.org/fulltextpdf.php?mno=32493 |
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