Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation
Bladder calculi associated or not with early crystalluria or salt deposits can be a common finding after reconstructive bladder surgery. The objective of this study was to characterize calculi and urine of domestic rabbits treated with mesenchymal adipose-derived stem cells (ADSCs) after partial uri...
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| Format: | Article |
| Language: | English |
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Universidade Estadual de Londrina
2016-04-01
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| Series: | Semina: Ciências Agrárias |
| Subjects: | |
| Online Access: | http://www.uel.br/revistas/uel/index.php/semagrarias/article/view/21193 |
| _version_ | 1819083850889822208 |
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| author | Saulo Tadeu Lemos Pinto Filho Fabíola Dalmolin Renata Medina Pinho Camila Feltrin Giglio Diandra Visentini Felin Kamila Lopes de Faria Aline da Rosa Vargas Maurício Veloso Brun Marcos André Braz Vaz Ney Luis Pippi |
| author_facet | Saulo Tadeu Lemos Pinto Filho Fabíola Dalmolin Renata Medina Pinho Camila Feltrin Giglio Diandra Visentini Felin Kamila Lopes de Faria Aline da Rosa Vargas Maurício Veloso Brun Marcos André Braz Vaz Ney Luis Pippi |
| author_sort | Saulo Tadeu Lemos Pinto Filho |
| collection | DOAJ |
| description | Bladder calculi associated or not with early crystalluria or salt deposits can be a common finding after reconstructive bladder surgery. The objective of this study was to characterize calculi and urine of domestic rabbits treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation. Twenty-four New Zealand White rabbits were submitted to surgery and treated postoperatively with cyclosporine or ADSCs for immunosuppression. There were no signs of graft rejection in either treatment group 30 days after surgery. Fewer animals presented bladder calculi in the ADSC treated group (33.3%) compared to the cyclosporine treated group (58.3%). Calcium was the predominant component of calculi in both groups. Urinalysis revealed no haematuria or bacteriuria in the ADSC group, in contrast to the results obtained for the cyclosporine group. ADSCs may be an attractive alternative to cyclosporine for immunosuppression after bladder allotransplantation. |
| first_indexed | 2024-12-21T20:39:07Z |
| format | Article |
| id | doaj.art-9d988d4e28ea426bb4e78a5ccee26c91 |
| institution | Directory Open Access Journal |
| issn | 1676-546X 1679-0359 |
| language | English |
| last_indexed | 2024-12-21T20:39:07Z |
| publishDate | 2016-04-01 |
| publisher | Universidade Estadual de Londrina |
| record_format | Article |
| series | Semina: Ciências Agrárias |
| spelling | doaj.art-9d988d4e28ea426bb4e78a5ccee26c912022-12-21T18:51:01ZengUniversidade Estadual de LondrinaSemina: Ciências Agrárias1676-546X1679-03592016-04-0137286787610.5433/1679-0359.2016v37n2p86713639Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantationSaulo Tadeu Lemos Pinto Filho0Fabíola Dalmolin1Renata Medina Pinho2Camila Feltrin Giglio3Diandra Visentini Felin4Kamila Lopes de Faria5Aline da Rosa Vargas6Maurício Veloso Brun7Marcos André Braz Vaz8Ney Luis Pippi9Universidade Federal de Santa MariaUniversidade Federal da Fronteira SulUniversidade Federal de Santa MariaClínica Veterinária Mundo AnimalUniversidade Federal de Santa MariaServiço de Rx e UltrassomPrograma de Residência Multiprofissional e em Área Profissional da SaúdeUniversidade Federal de Santa MariaUniversidade Federal de Santa MariaUniversidade Federal de Santa MariaBladder calculi associated or not with early crystalluria or salt deposits can be a common finding after reconstructive bladder surgery. The objective of this study was to characterize calculi and urine of domestic rabbits treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation. Twenty-four New Zealand White rabbits were submitted to surgery and treated postoperatively with cyclosporine or ADSCs for immunosuppression. There were no signs of graft rejection in either treatment group 30 days after surgery. Fewer animals presented bladder calculi in the ADSC treated group (33.3%) compared to the cyclosporine treated group (58.3%). Calcium was the predominant component of calculi in both groups. Urinalysis revealed no haematuria or bacteriuria in the ADSC group, in contrast to the results obtained for the cyclosporine group. ADSCs may be an attractive alternative to cyclosporine for immunosuppression after bladder allotransplantation.http://www.uel.br/revistas/uel/index.php/semagrarias/article/view/21193BexigaCirurgiaCTMUrolitíase. |
| spellingShingle | Saulo Tadeu Lemos Pinto Filho Fabíola Dalmolin Renata Medina Pinho Camila Feltrin Giglio Diandra Visentini Felin Kamila Lopes de Faria Aline da Rosa Vargas Maurício Veloso Brun Marcos André Braz Vaz Ney Luis Pippi Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation Semina: Ciências Agrárias Bexiga Cirurgia CTM Urolitíase. |
| title | Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation |
| title_full | Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation |
| title_fullStr | Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation |
| title_full_unstemmed | Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation |
| title_short | Characterization of bladder calculi and urinalysis in rabbits (Oryctolagus cuniculus) treated with mesenchymal adipose-derived stem cells (ADSCs) after partial urinary bladder allotransplantation |
| title_sort | characterization of bladder calculi and urinalysis in rabbits oryctolagus cuniculus treated with mesenchymal adipose derived stem cells adscs after partial urinary bladder allotransplantation |
| topic | Bexiga Cirurgia CTM Urolitíase. |
| url | http://www.uel.br/revistas/uel/index.php/semagrarias/article/view/21193 |
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