Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction
A semisynthesis of 6<i>β</i>-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of <i>Caesalpinia platyloba</i> by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where a non-n...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Chemistry Proceedings |
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| Online Access: | https://www.mdpi.com/2673-4583/12/1/24 |
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| author | Gabriela Servín-García Luis Chacón-García Joaquín González-Marrero Mariana Macías-Alonso Mario A. Gómez-Hurtado Gabriela Rodríguez-García Rosa E. del Río Carlos J. Cortés-García |
| author_facet | Gabriela Servín-García Luis Chacón-García Joaquín González-Marrero Mariana Macías-Alonso Mario A. Gómez-Hurtado Gabriela Rodríguez-García Rosa E. del Río Carlos J. Cortés-García |
| author_sort | Gabriela Servín-García |
| collection | DOAJ |
| description | A semisynthesis of 6<i>β</i>-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of <i>Caesalpinia platyloba</i> by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where a non-natural product such as 1,5-disusbtituted tetrazole has been linked to a natural product or derivate of a natural product, and beyond the biological relevance that the target molecules present, this work contributes to the area of natural products as well as multicomponent reactions. |
| first_indexed | 2024-03-11T02:38:06Z |
| format | Article |
| id | doaj.art-9d997e3725a945e4a47e97aa2d3fb1f5 |
| institution | Directory Open Access Journal |
| issn | 2673-4583 |
| language | English |
| last_indexed | 2024-03-11T02:38:06Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Chemistry Proceedings |
| spelling | doaj.art-9d997e3725a945e4a47e97aa2d3fb1f52023-11-18T09:47:56ZengMDPI AGChemistry Proceedings2673-45832022-11-011212410.3390/ecsoc-26-13552Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent ReactionGabriela Servín-García0Luis Chacón-García1Joaquín González-Marrero2Mariana Macías-Alonso3Mario A. Gómez-Hurtado4Gabriela Rodríguez-García5Rosa E. del Río6Carlos J. Cortés-García7Laboratorio de Diseño Molecular, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, MexicoLaboratorio de Diseño Molecular, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, MexicoInstituto Politécnico Nacional, Unidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato, Av. Mineral de Valenciana 200 Col. Fracc. Industrial Puerto Interior, Silao 36275, MexicoInstituto Politécnico Nacional, Unidad Profesional Interdisciplinaria de Ingeniería Campus Guanajuato, Av. Mineral de Valenciana 200 Col. Fracc. Industrial Puerto Interior, Silao 36275, MexicoLaboratorio de Química de Productos Naturales, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, MexicoLaboratorio de Química de Productos Naturales, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, MexicoLaboratorio de Química de Productos Naturales, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, MexicoLaboratorio de Química de Productos Naturales, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Ciudad Universitaria, Morelia 58030, MexicoA semisynthesis of 6<i>β</i>-acetoxyvouacapane-1,5-disusbtituted tetrazoles derivatives from the leaves of <i>Caesalpinia platyloba</i> by using the Ugi-azide multicomponent reaction as a key step reaction is described. To our knowledge, this is the first report where a non-natural product such as 1,5-disusbtituted tetrazole has been linked to a natural product or derivate of a natural product, and beyond the biological relevance that the target molecules present, this work contributes to the area of natural products as well as multicomponent reactions.https://www.mdpi.com/2673-4583/12/1/246<i>β</i>-acetoxyvouacapane1,5-disusbtituted tetrazolesugi-azideisocyanidessemisynthesis |
| spellingShingle | Gabriela Servín-García Luis Chacón-García Joaquín González-Marrero Mariana Macías-Alonso Mario A. Gómez-Hurtado Gabriela Rodríguez-García Rosa E. del Río Carlos J. Cortés-García Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction Chemistry Proceedings 6<i>β</i>-acetoxyvouacapane 1,5-disusbtituted tetrazoles ugi-azide isocyanides semisynthesis |
| title | Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction |
| title_full | Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction |
| title_fullStr | Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction |
| title_full_unstemmed | Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction |
| title_short | Semisynthesis of 6<i>β</i>-Acetoxyvouacapane Derivatives via the Ugi-Azide Multicomponent Reaction |
| title_sort | semisynthesis of 6 i β i acetoxyvouacapane derivatives via the ugi azide multicomponent reaction |
| topic | 6<i>β</i>-acetoxyvouacapane 1,5-disusbtituted tetrazoles ugi-azide isocyanides semisynthesis |
| url | https://www.mdpi.com/2673-4583/12/1/24 |
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