Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh
OBJECTIVE: To evaluate vaccine effectiveness and to assess risk factors for measles in Dhaka, Bangladesh. METHOD: A case-control study, involving 198 cases with 783 age-matched neighbourhood controls and 120 measles cases with 365 age-matched hospital controls, was conducted in 1995-96 in three larg...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The World Health Organization
2002-01-01
|
| Series: | Bulletin of the World Health Organization |
| Subjects: | |
| Online Access: | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862002001000005 |
| _version_ | 1827337075535380480 |
|---|---|
| author | Akramuzzaman Syed M. Cutts Felicity T. Hossain Md J. Wahedi Obaidullah K. Nahar Nazmun Islam Darul Shaha Narayan C. Mahalanabis Dilip |
| author_facet | Akramuzzaman Syed M. Cutts Felicity T. Hossain Md J. Wahedi Obaidullah K. Nahar Nazmun Islam Darul Shaha Narayan C. Mahalanabis Dilip |
| author_sort | Akramuzzaman Syed M. |
| collection | DOAJ |
| description | OBJECTIVE: To evaluate vaccine effectiveness and to assess risk factors for measles in Dhaka, Bangladesh. METHOD: A case-control study, involving 198 cases with 783 age-matched neighbourhood controls and 120 measles cases with 365 age-matched hospital controls, was conducted in 1995-96 in three large hospitals in Dhaka. FINDINGS: Measles vaccine effectiveness was estimated at 80% (95% confidence interval (CI) = 60-90%) using neighbourhood controls; very similar results were obtained using hospital controls. Visits to a health facility 7-21 days before onset of any symptoms were associated with increased risk of measles compared with neighbourhood (adjusted odds ratio (OR) = 7.0, 95% CI = 4.2-11.6) or hospital (adjusted OR = 1.7, 95% CI = 1.01-2.8) controls. Cases were more likely than controls to come from a household where more than one child lived (adjusted OR = 1.6, 95% CI = 1.1-2.5 versus neighbourhood controls; adjusted OR = 1.8, 95% CI = 1.02-3.0 versus hospital controls). CONCLUSIONS: To improve measles control in urban Dhaka missed immunization opportunities must be reduced in all health care facilities by following WHO guidelines. For measles elimination, more than one dose of vaccine would be required. |
| first_indexed | 2024-03-07T18:45:35Z |
| format | Article |
| id | doaj.art-9d9a22e868c34ff284068e5d607ccd2e |
| institution | Directory Open Access Journal |
| issn | 0042-9686 |
| language | English |
| last_indexed | 2024-03-07T18:45:35Z |
| publishDate | 2002-01-01 |
| publisher | The World Health Organization |
| record_format | Article |
| series | Bulletin of the World Health Organization |
| spelling | doaj.art-9d9a22e868c34ff284068e5d607ccd2e2024-03-02T02:42:11ZengThe World Health OrganizationBulletin of the World Health Organization0042-96862002-01-018010776782Measles vaccine effectiveness and risk factors for measles in Dhaka, BangladeshAkramuzzaman Syed M.Cutts Felicity T.Hossain Md J.Wahedi Obaidullah K.Nahar NazmunIslam DarulShaha Narayan C.Mahalanabis DilipOBJECTIVE: To evaluate vaccine effectiveness and to assess risk factors for measles in Dhaka, Bangladesh. METHOD: A case-control study, involving 198 cases with 783 age-matched neighbourhood controls and 120 measles cases with 365 age-matched hospital controls, was conducted in 1995-96 in three large hospitals in Dhaka. FINDINGS: Measles vaccine effectiveness was estimated at 80% (95% confidence interval (CI) = 60-90%) using neighbourhood controls; very similar results were obtained using hospital controls. Visits to a health facility 7-21 days before onset of any symptoms were associated with increased risk of measles compared with neighbourhood (adjusted odds ratio (OR) = 7.0, 95% CI = 4.2-11.6) or hospital (adjusted OR = 1.7, 95% CI = 1.01-2.8) controls. Cases were more likely than controls to come from a household where more than one child lived (adjusted OR = 1.6, 95% CI = 1.1-2.5 versus neighbourhood controls; adjusted OR = 1.8, 95% CI = 1.02-3.0 versus hospital controls). CONCLUSIONS: To improve measles control in urban Dhaka missed immunization opportunities must be reduced in all health care facilities by following WHO guidelines. For measles elimination, more than one dose of vaccine would be required.http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862002001000005Measles vaccine/therapeutic useMeasles/etiologyCross infectionImmunizationRisk factorsSocioeconomic factorsCase-control studiesOdds ratioBangladesh |
| spellingShingle | Akramuzzaman Syed M. Cutts Felicity T. Hossain Md J. Wahedi Obaidullah K. Nahar Nazmun Islam Darul Shaha Narayan C. Mahalanabis Dilip Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh Bulletin of the World Health Organization Measles vaccine/therapeutic use Measles/etiology Cross infection Immunization Risk factors Socioeconomic factors Case-control studies Odds ratio Bangladesh |
| title | Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh |
| title_full | Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh |
| title_fullStr | Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh |
| title_full_unstemmed | Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh |
| title_short | Measles vaccine effectiveness and risk factors for measles in Dhaka, Bangladesh |
| title_sort | measles vaccine effectiveness and risk factors for measles in dhaka bangladesh |
| topic | Measles vaccine/therapeutic use Measles/etiology Cross infection Immunization Risk factors Socioeconomic factors Case-control studies Odds ratio Bangladesh |
| url | http://www.scielosp.org/scielo.php?script=sci_arttext&pid=S0042-96862002001000005 |
| work_keys_str_mv | AT akramuzzamansyedm measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT cuttsfelicityt measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT hossainmdj measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT wahediobaidullahk measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT naharnazmun measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT islamdarul measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT shahanarayanc measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh AT mahalanabisdilip measlesvaccineeffectivenessandriskfactorsformeaslesindhakabangladesh |