Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study
Background: Highly active antiretroviral therapy regimens have resulted in the systemic/clinical healing for human immune deficiency virus-infected patients but the consequence of antiretroviral therapy on the whole quality of life has become a major concern. The current study correlates the relatio...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2013-01-01
|
| Series: | Journal of Global Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.jgid.org/article.asp?issn=0974-777X;year=2013;volume=5;issue=3;spage=104;epage=109;aulast=Singh |
| _version_ | 1818986230614851584 |
|---|---|
| author | Harminder Singh Kamalpreet Kaur Navin Dulhani Akash Bansal Bithika N Kumar Vinod Kumar Singh Chouhan |
| author_facet | Harminder Singh Kamalpreet Kaur Navin Dulhani Akash Bansal Bithika N Kumar Vinod Kumar Singh Chouhan |
| author_sort | Harminder Singh |
| collection | DOAJ |
| description | Background: Highly active antiretroviral therapy regimens have resulted in the systemic/clinical healing for human immune deficiency virus-infected patients but the consequence of antiretroviral therapy on the whole quality of life has become a major concern. The current study correlates the relationship of quality of life with successful highly active antiretroviral therapy. Aim : To determine the health-related quality of life in human immune deficiency virus-infected patients on highly active anti-retroviral therapy regimen in tribal region of Chhattisgarh. Design: An open label prospective study. Materials and Methods: Health-related quality of life was assessed using a standardized questionnaire, the Medical Outcomes Survey Short Form 36. Physical health summary scores and mental health summary scores were compared of pre-Highly Active Anti-Retroviral Therapy (at baseline) and post 12 months of therapy. Results: The increase in CD4 cell counts was extremely significant (P < 0.0001). The Physical Composite Summary (P value = 0.0003) improved significantly, whereas the Mental Composite Summary (with a baseline value of 40.7), post 12 months, was calculated as 42.8 (P value = 0.2371) and was statistically not significant. Conclusion: Efficacy measurement is the key ingredient of highly active anti-retroviral therapy, which must also include assessment of health-related quality of life to maximize the holistic approach towards disease. |
| first_indexed | 2024-12-20T18:47:30Z |
| format | Article |
| id | doaj.art-9d9a22f7c6524b25bcf96a1662d7e3ad |
| institution | Directory Open Access Journal |
| issn | 0974-777X |
| language | English |
| last_indexed | 2024-12-20T18:47:30Z |
| publishDate | 2013-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Global Infectious Diseases |
| spelling | doaj.art-9d9a22f7c6524b25bcf96a1662d7e3ad2022-12-21T19:29:40ZengWolters Kluwer Medknow PublicationsJournal of Global Infectious Diseases0974-777X2013-01-015310410910.4103/0974-777X.116870Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective studyHarminder SinghKamalpreet KaurNavin DulhaniAkash BansalBithika N KumarVinod Kumar Singh ChouhanBackground: Highly active antiretroviral therapy regimens have resulted in the systemic/clinical healing for human immune deficiency virus-infected patients but the consequence of antiretroviral therapy on the whole quality of life has become a major concern. The current study correlates the relationship of quality of life with successful highly active antiretroviral therapy. Aim : To determine the health-related quality of life in human immune deficiency virus-infected patients on highly active anti-retroviral therapy regimen in tribal region of Chhattisgarh. Design: An open label prospective study. Materials and Methods: Health-related quality of life was assessed using a standardized questionnaire, the Medical Outcomes Survey Short Form 36. Physical health summary scores and mental health summary scores were compared of pre-Highly Active Anti-Retroviral Therapy (at baseline) and post 12 months of therapy. Results: The increase in CD4 cell counts was extremely significant (P < 0.0001). The Physical Composite Summary (P value = 0.0003) improved significantly, whereas the Mental Composite Summary (with a baseline value of 40.7), post 12 months, was calculated as 42.8 (P value = 0.2371) and was statistically not significant. Conclusion: Efficacy measurement is the key ingredient of highly active anti-retroviral therapy, which must also include assessment of health-related quality of life to maximize the holistic approach towards disease.http://www.jgid.org/article.asp?issn=0974-777X;year=2013;volume=5;issue=3;spage=104;epage=109;aulast=SinghHighly active antiretroviral therapyHealth-related quality of lifeMedical outcomes survey short form 36 questionnaireTribal HIV patients |
| spellingShingle | Harminder Singh Kamalpreet Kaur Navin Dulhani Akash Bansal Bithika N Kumar Vinod Kumar Singh Chouhan Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study Journal of Global Infectious Diseases Highly active antiretroviral therapy Health-related quality of life Medical outcomes survey short form 36 questionnaire Tribal HIV patients |
| title | Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study |
| title_full | Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study |
| title_fullStr | Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study |
| title_full_unstemmed | Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study |
| title_short | Assessment of quality of life in a cohort of newly diagnosed patients on haart regimen, in resource restricted tribal region of chhattisgarh, India: A prospective study |
| title_sort | assessment of quality of life in a cohort of newly diagnosed patients on haart regimen in resource restricted tribal region of chhattisgarh india a prospective study |
| topic | Highly active antiretroviral therapy Health-related quality of life Medical outcomes survey short form 36 questionnaire Tribal HIV patients |
| url | http://www.jgid.org/article.asp?issn=0974-777X;year=2013;volume=5;issue=3;spage=104;epage=109;aulast=Singh |
| work_keys_str_mv | AT harmindersingh assessmentofqualityoflifeinacohortofnewlydiagnosedpatientsonhaartregimeninresourcerestrictedtribalregionofchhattisgarhindiaaprospectivestudy AT kamalpreetkaur assessmentofqualityoflifeinacohortofnewlydiagnosedpatientsonhaartregimeninresourcerestrictedtribalregionofchhattisgarhindiaaprospectivestudy AT navindulhani assessmentofqualityoflifeinacohortofnewlydiagnosedpatientsonhaartregimeninresourcerestrictedtribalregionofchhattisgarhindiaaprospectivestudy AT akashbansal assessmentofqualityoflifeinacohortofnewlydiagnosedpatientsonhaartregimeninresourcerestrictedtribalregionofchhattisgarhindiaaprospectivestudy AT bithikankumar assessmentofqualityoflifeinacohortofnewlydiagnosedpatientsonhaartregimeninresourcerestrictedtribalregionofchhattisgarhindiaaprospectivestudy AT vinodkumarsinghchouhan assessmentofqualityoflifeinacohortofnewlydiagnosedpatientsonhaartregimeninresourcerestrictedtribalregionofchhattisgarhindiaaprospectivestudy |