Characterization of organic contaminants in hair for biomonitoring purposes
Biological monitoring is one way to assess human exposure to contaminants. Blood and urine are often used as biological matrices, but hair is an innovative and effective tool for quantifying more biomarkers over a wider exposure window. In order to improve the use of hair in exposure assessment, thi...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
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| Series: | Environment International |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0160412024000059 |
| _version_ | 1797349448723988480 |
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| author | Ashna Lallmahomed Fabien Mercier Nathalie Costet Clémence Fillol Nathalie Bonvallot Barbara Le Bot |
| author_facet | Ashna Lallmahomed Fabien Mercier Nathalie Costet Clémence Fillol Nathalie Bonvallot Barbara Le Bot |
| author_sort | Ashna Lallmahomed |
| collection | DOAJ |
| description | Biological monitoring is one way to assess human exposure to contaminants. Blood and urine are often used as biological matrices, but hair is an innovative and effective tool for quantifying more biomarkers over a wider exposure window. In order to improve the use of hair in exposure assessment, this article identifies relevant compounds in the literature to investigate hair contamination. Statistical analysis was performed to correlate the physical-chemical properties of the relevant compounds and their concentration levels in hair. Phthalates, pyrethroids and organophosphate flame retardants were chosen for further study of the interpretation of hair measurements for exposure assessment. No significant correlation was found between the average concentration levels in the literature and the physical-chemical properties of the selected compounds. This work also explores the properties of hair and the analytical process that may impact the quantification of organic contaminants in hair. The sample preparation method (sampling, storage, washing) were also studied and adaptations were suggested to improve the existing methods. |
| first_indexed | 2024-03-08T12:30:23Z |
| format | Article |
| id | doaj.art-9da1809ee8a444ab8c5a47ce62166f71 |
| institution | Directory Open Access Journal |
| issn | 0160-4120 |
| language | English |
| last_indexed | 2024-03-08T12:30:23Z |
| publishDate | 2024-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Environment International |
| spelling | doaj.art-9da1809ee8a444ab8c5a47ce62166f712024-01-22T04:15:36ZengElsevierEnvironment International0160-41202024-01-01183108419Characterization of organic contaminants in hair for biomonitoring purposesAshna Lallmahomed0Fabien Mercier1Nathalie Costet2Clémence Fillol3Nathalie Bonvallot4Barbara Le Bot5Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, FranceUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, FranceUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, FranceDirection of Environmental and Occupational Health, Santé publique France, Saint Maurice Cedex, FranceUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, FranceUniv Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, F-35000 Rennes, France; Corresponding author.Biological monitoring is one way to assess human exposure to contaminants. Blood and urine are often used as biological matrices, but hair is an innovative and effective tool for quantifying more biomarkers over a wider exposure window. In order to improve the use of hair in exposure assessment, this article identifies relevant compounds in the literature to investigate hair contamination. Statistical analysis was performed to correlate the physical-chemical properties of the relevant compounds and their concentration levels in hair. Phthalates, pyrethroids and organophosphate flame retardants were chosen for further study of the interpretation of hair measurements for exposure assessment. No significant correlation was found between the average concentration levels in the literature and the physical-chemical properties of the selected compounds. This work also explores the properties of hair and the analytical process that may impact the quantification of organic contaminants in hair. The sample preparation method (sampling, storage, washing) were also studied and adaptations were suggested to improve the existing methods.http://www.sciencedirect.com/science/article/pii/S0160412024000059Hair analysisOrganic contaminantExposure assessmentBiomonitoring |
| spellingShingle | Ashna Lallmahomed Fabien Mercier Nathalie Costet Clémence Fillol Nathalie Bonvallot Barbara Le Bot Characterization of organic contaminants in hair for biomonitoring purposes Environment International Hair analysis Organic contaminant Exposure assessment Biomonitoring |
| title | Characterization of organic contaminants in hair for biomonitoring purposes |
| title_full | Characterization of organic contaminants in hair for biomonitoring purposes |
| title_fullStr | Characterization of organic contaminants in hair for biomonitoring purposes |
| title_full_unstemmed | Characterization of organic contaminants in hair for biomonitoring purposes |
| title_short | Characterization of organic contaminants in hair for biomonitoring purposes |
| title_sort | characterization of organic contaminants in hair for biomonitoring purposes |
| topic | Hair analysis Organic contaminant Exposure assessment Biomonitoring |
| url | http://www.sciencedirect.com/science/article/pii/S0160412024000059 |
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