Ischemic neuronal death in the rat hippocampus: the calpain–calpastatin–caspase hypothesis

Inappropriate imbalances between proteases and protease inhibitors are known to occur under cerebral ischemia and neurodegenerative processes, and could be contributors to various diseases that are characterized by excessive (ischemia, AIDS) or inadequate (cancer, autoimmunity) cell death. For insta...

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Bibliographic Details
Main Author: A Rami
Format: Article
Language:English
Published: Elsevier 2003-07-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996103000184