Abnormal sodium and water homeostasis in mice with defective heparan sulfate polymerization.

Glycosaminoglycans in the skin interstitium and endothelial surface layer have been shown to be involved in local sodium accumulation without commensurate water retention. Dysfunction of heparan sulfate glycosaminoglycans may therefore disrupt sodium and water homeostasis. In this study, we investig...

Полное описание

Библиографические подробности
Главные авторы: Rik H G Olde Engberink, Judith de Vos, Angela van Weert, Yahua Zhang, Naomi van Vlies, Bert-Jan H van den Born, Jens M Titze, Ed van Bavel, Liffert Vogt
Формат: Статья
Язык:English
Опубликовано: Public Library of Science (PLoS) 2019-01-01
Серии:PLoS ONE
Online-ссылка:https://doi.org/10.1371/journal.pone.0220333